Handedness and the geometry and hemodynamics of the branches of the aortic arch

 

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dc.contributor.advisor Solms, Mark en_ZA
dc.contributor.author Jansen van Vuuren, Anica en_ZA
dc.date.accessioned 2015-05-26T14:19:13Z
dc.date.available 2015-05-26T14:19:13Z
dc.date.issued 2014 en_ZA
dc.identifier.citation Jansen van Vuuren, A. 2014. Handedness and the geometry and hemodynamics of the branches of the aortic arch. University of Cape Town. en_ZA
dc.identifier.uri http://hdl.handle.net/11427/12883
dc.description Includes bibliographical references. en_ZA
dc.description.abstract Asymmetry in the vasculature arising from the human aortic arch seems the obvious place to look for an anatomical basis for lateralized cerebral functions, but this relationship has never systematically been investigated. This study explored the relationship between handedness and the anatomical and hemodynamic characteristics of the carotid arteries, analysing potential asymmetries between the left and right common, internal and external carotid arteries in leftha-nded versus right-handed individuals. The study is separated into two chapters: geometric (n = 199) and hemodynamic (n = 234). A revised version of the Edinburgh Handedness Inventory classified all participants into relevant handedness preference categories. For the geometric study, detailed measurements of the common carotid arteries in computed tomography angiography scans were obtained using Radiant DICOM Viewer (64-bit) imaging software. Selected geometric parameters of the vessels measured included minimum, mean, and maximum diameters, length, angle and calculated resistance to blood flow. Cases of unconventional branching patterns were analysed separately. For the hemodynamic study, Speed and Accuracy Target Tests quantified the participants’ handedness performance. Doppler ultrasound was performed using the Vivid i GE Ultrasound system, on the common, internal and external carotid arteries. Hemodynamic parameters of the Doppler waveform were recorded, including Peak systolic and end-diastolic velocity, Resistive index, Pulsatility index, volume flow rate, and vessel diameter. The data was analysed with mixed design ANOVAs, discriminant function analyses, multiple regressions, and paired and independent t-tests, to investigate the asymmetries and predictive properties of the measured variables en_ZA
dc.language.iso eng en_ZA
dc.subject.other Neuropsychology en_ZA
dc.title Handedness and the geometry and hemodynamics of the branches of the aortic arch en_ZA
dc.type Master Thesis
uct.type.publication Research en_ZA
uct.type.resource Thesis en_ZA
dc.publisher.institution University of Cape Town
dc.publisher.faculty Faculty of Humanities en_ZA
dc.publisher.department Department of Psychology en_ZA
dc.type.qualificationlevel Masters
dc.type.qualificationname MA en_ZA
uct.type.filetype Text
uct.type.filetype Image
dc.identifier.apacitation Jansen van Vuuren, A. (2014). <i>Handedness and the geometry and hemodynamics of the branches of the aortic arch</i>. (Thesis). University of Cape Town ,Faculty of Humanities ,Department of Psychology. Retrieved from http://hdl.handle.net/11427/12883 en_ZA
dc.identifier.chicagocitation Jansen van Vuuren, Anica. <i>"Handedness and the geometry and hemodynamics of the branches of the aortic arch."</i> Thesis., University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2014. http://hdl.handle.net/11427/12883 en_ZA
dc.identifier.vancouvercitation Jansen van Vuuren A. Handedness and the geometry and hemodynamics of the branches of the aortic arch. [Thesis]. University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2014 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/12883 en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Jansen van Vuuren, Anica AB - Asymmetry in the vasculature arising from the human aortic arch seems the obvious place to look for an anatomical basis for lateralized cerebral functions, but this relationship has never systematically been investigated. This study explored the relationship between handedness and the anatomical and hemodynamic characteristics of the carotid arteries, analysing potential asymmetries between the left and right common, internal and external carotid arteries in leftha-nded versus right-handed individuals. The study is separated into two chapters: geometric (n = 199) and hemodynamic (n = 234). A revised version of the Edinburgh Handedness Inventory classified all participants into relevant handedness preference categories. For the geometric study, detailed measurements of the common carotid arteries in computed tomography angiography scans were obtained using Radiant DICOM Viewer (64-bit) imaging software. Selected geometric parameters of the vessels measured included minimum, mean, and maximum diameters, length, angle and calculated resistance to blood flow. Cases of unconventional branching patterns were analysed separately. For the hemodynamic study, Speed and Accuracy Target Tests quantified the participants’ handedness performance. Doppler ultrasound was performed using the Vivid i GE Ultrasound system, on the common, internal and external carotid arteries. Hemodynamic parameters of the Doppler waveform were recorded, including Peak systolic and end-diastolic velocity, Resistive index, Pulsatility index, volume flow rate, and vessel diameter. The data was analysed with mixed design ANOVAs, discriminant function analyses, multiple regressions, and paired and independent t-tests, to investigate the asymmetries and predictive properties of the measured variables DA - 2014 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Handedness and the geometry and hemodynamics of the branches of the aortic arch TI - Handedness and the geometry and hemodynamics of the branches of the aortic arch UR - http://hdl.handle.net/11427/12883 ER - en_ZA


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