Handedness and the geometry and hemodynamics of the branches of the aortic arch

Simple item page
dc.contributor.advisorSolms, Marken_ZA
dc.contributor.authorJansen van Vuuren, Anicaen_ZA
dc.date.accessioned2015-05-26T14:19:13Z
dc.date.available2015-05-26T14:19:13Z
dc.date.issued2014en_ZA
dc.descriptionIncludes bibliographical references.en_ZA
dc.description.abstractAsymmetry in the vasculature arising from the human aortic arch seems the obvious place to look for an anatomical basis for lateralized cerebral functions, but this relationship has never systematically been investigated. This study explored the relationship between handedness and the anatomical and hemodynamic characteristics of the carotid arteries, analysing potential asymmetries between the left and right common, internal and external carotid arteries in leftha-nded versus right-handed individuals. The study is separated into two chapters: geometric (n = 199) and hemodynamic (n = 234). A revised version of the Edinburgh Handedness Inventory classified all participants into relevant handedness preference categories. For the geometric study, detailed measurements of the common carotid arteries in computed tomography angiography scans were obtained using Radiant DICOM Viewer (64-bit) imaging software. Selected geometric parameters of the vessels measured included minimum, mean, and maximum diameters, length, angle and calculated resistance to blood flow. Cases of unconventional branching patterns were analysed separately. For the hemodynamic study, Speed and Accuracy Target Tests quantified the participants’ handedness performance. Doppler ultrasound was performed using the Vivid i GE Ultrasound system, on the common, internal and external carotid arteries. Hemodynamic parameters of the Doppler waveform were recorded, including Peak systolic and end-diastolic velocity, Resistive index, Pulsatility index, volume flow rate, and vessel diameter. The data was analysed with mixed design ANOVAs, discriminant function analyses, multiple regressions, and paired and independent t-tests, to investigate the asymmetries and predictive properties of the measured variablesen_ZA
dc.identifier.apacitationJansen van Vuuren, A. (2014). <i>Handedness and the geometry and hemodynamics of the branches of the aortic arch</i>. (Thesis). University of Cape Town ,Faculty of Humanities ,Department of Psychology. Retrieved from http://hdl.handle.net/11427/12883en_ZA
dc.identifier.chicagocitationJansen van Vuuren, Anica. <i>"Handedness and the geometry and hemodynamics of the branches of the aortic arch."</i> Thesis., University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2014. http://hdl.handle.net/11427/12883en_ZA
dc.identifier.citationJansen van Vuuren, A. 2014. Handedness and the geometry and hemodynamics of the branches of the aortic arch. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Jansen van Vuuren, Anica AB - Asymmetry in the vasculature arising from the human aortic arch seems the obvious place to look for an anatomical basis for lateralized cerebral functions, but this relationship has never systematically been investigated. This study explored the relationship between handedness and the anatomical and hemodynamic characteristics of the carotid arteries, analysing potential asymmetries between the left and right common, internal and external carotid arteries in leftha-nded versus right-handed individuals. The study is separated into two chapters: geometric (n = 199) and hemodynamic (n = 234). A revised version of the Edinburgh Handedness Inventory classified all participants into relevant handedness preference categories. For the geometric study, detailed measurements of the common carotid arteries in computed tomography angiography scans were obtained using Radiant DICOM Viewer (64-bit) imaging software. Selected geometric parameters of the vessels measured included minimum, mean, and maximum diameters, length, angle and calculated resistance to blood flow. Cases of unconventional branching patterns were analysed separately. For the hemodynamic study, Speed and Accuracy Target Tests quantified the participants’ handedness performance. Doppler ultrasound was performed using the Vivid i GE Ultrasound system, on the common, internal and external carotid arteries. Hemodynamic parameters of the Doppler waveform were recorded, including Peak systolic and end-diastolic velocity, Resistive index, Pulsatility index, volume flow rate, and vessel diameter. The data was analysed with mixed design ANOVAs, discriminant function analyses, multiple regressions, and paired and independent t-tests, to investigate the asymmetries and predictive properties of the measured variables DA - 2014 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Handedness and the geometry and hemodynamics of the branches of the aortic arch TI - Handedness and the geometry and hemodynamics of the branches of the aortic arch UR - http://hdl.handle.net/11427/12883 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/12883
dc.identifier.vancouvercitationJansen van Vuuren A. Handedness and the geometry and hemodynamics of the branches of the aortic arch. [Thesis]. University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2014 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/12883en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Psychologyen_ZA
dc.publisher.facultyFaculty of Humanitiesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherNeuropsychologyen_ZA
dc.titleHandedness and the geometry and hemodynamics of the branches of the aortic archen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMAen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
thesis_hum_2014_jansen_van_vuuren_a.pdf
Size:
4.45 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Masters