Browsing by Subject "Propanolol"

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    The first-pass extraction of pindolol in comparison with propranolol in rat liver
    (1979) Basset, Helen Margaret; Folb, Peter I
    Reports in the literature have shown that in man propranolol has a larger first-pass effect (70%) than pindolol (13%). The aim of this research was to make a direct comparison of first-pass extraction and other pharmacokinetic parameters of these drugs under identical experimental conditions by means of an isolated rat liver perfusion model.