Browsing by Subject "Nifedipine"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Open Access
    Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration
    (1987) Lindow, S W; Davey, D A
    Nifedipine, in a 5mg sublingual acute administration, causes a significant fall in the systolic, diastolic and mean arterial pressure in a mixed group of pregnant hypertensives. A concurrent, significant rise in the pulse rate was seen. The utero-placental blood flow index, which is a measure of utero-placental blood flow, was not significantly reduced following the administration of Nifedipine or a placebo. The utero-placental blood flow index was found to be a consistent measure of utero-placental blood flow in resting patients. In the absence of serious side-effects it can be concluded that Nifedipine is a safe therapy in the acute treatment of hypertensive states in pregnancy.