Browsing by Author "Mbele, Prisca"
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- ItemOpen AccessEvaluation of a reverse tetracycline inducible system in recombinant BCG to improve stability and immunogenicity(2011) Mbele, Prisca; Chapman, Ros; Williamson, Anna-LiseThe aim of this study is to utilise the tetracycline dependent gene regulation system to down-regulate recombinant antigen expression in BCG during the expansion of seed stocks and up-regulate expression prior to or post vaccination.