The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update

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dc.contributor.authorMaurer, Marcus
dc.contributor.authorMagerl, Markus
dc.contributor.authorAnsotegui, Ignacio
dc.contributor.authorAygören-Pürsün, Emel
dc.contributor.authorBetschel, Stephen
dc.contributor.authorBork, Konrad
dc.contributor.authorBowen, Tom
dc.contributor.authorBoysen, Henrik B
dc.contributor.authorFarkas, Henriette
dc.contributor.authorGrumach, Anete S
dc.contributor.authorHide, Michihiro
dc.contributor.authorKatelaris, Constance
dc.contributor.authorLockey, Richard
dc.contributor.authorLonghurst, Hilary
dc.contributor.authorLumry, William R.
dc.contributor.authorMartinez-Saguer, Inmaculada
dc.contributor.authorMoldovan, Dumitru
dc.contributor.authorNast, Alexander
dc.contributor.authorPawankar, Ruby
dc.contributor.authorPotter, Paul
dc.contributor.authorRiedl, Marc
dc.contributor.authorRitchie, Bruce
dc.contributor.authorRosenwasser, Lanny
dc.contributor.authorSánchez-Borges, Mario
dc.contributor.authorZhi, Yuxiang
dc.contributor.authorZuraw, Bruce
dc.contributor.authorCraig, Timothy
dc.date.accessioned2018-05-04T07:46:03Z
dc.date.available2018-05-04T07:46:03Z
dc.date.issued2018-02-27
dc.date.updated2018-04-09T15:10:28Z
dc.description.abstractHereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and appropriate therapy are essential. This update and revision of the global guideline for HAE provides up-to-date consensus recommendations for the management of HAE. In the development of this update and revision of the guideline, an international expert panel reviewed the existing evidence and developed 20 recommendations that were discussed, finalized and consented during the guideline consensus conference in June 2016 in Vienna. The final version of this update and revision of the guideline incorporates the contributions of a board of expert reviewers and the endorsing societies. The goal of this guideline update and revision is to provide clinicians and their patients with guidance that will assist them in making rational decisions in the management of HAE with deficient C1-inhibitor (type 1) and HAE with dysfunctional C1-inhibitor (type 2). The key clinical questions covered by these recommendations are: 1) How should HAE-1/2 be defined and classified?, 2) How should HAE-1/2 be diagnosed?, 3) Should HAE-1/2 patients receive prophylactic and/or on-demand treatment and what treatment options should be used?, 4) Should HAE-1/2 management be different for special HAE-1/2 patient groups such as pregnant/lactating women or children?, and 5) Should HAE-1/2 management incorporate self-administration of therapies and patient support measures? This article is co-published with permission in Allergy and the World Allergy Organization Journal.
dc.identifier.apacitationMaurer, M., Magerl, M., Ansotegui, I., Aygören-Pürsün, E., Betschel, S., Bork, K., ... Craig, T. (2018). The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update. <i>World Allergy Organization Journal</i>, http://hdl.handle.net/11427/27926en_ZA
dc.identifier.chicagocitationMaurer, Marcus, Markus Magerl, Ignacio Ansotegui, Emel Aygören-Pürsün, Stephen Betschel, Konrad Bork, Tom Bowen, et al "The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update." <i>World Allergy Organization Journal</i> (2018) http://hdl.handle.net/11427/27926en_ZA
dc.identifier.citationWorld Allergy Organization Journal. 2018 Feb 27;11(1):5
dc.identifier.ris TY - Journal Article AU - Maurer, Marcus AU - Magerl, Markus AU - Ansotegui, Ignacio AU - Aygören-Pürsün, Emel AU - Betschel, Stephen AU - Bork, Konrad AU - Bowen, Tom AU - Boysen, Henrik B AU - Farkas, Henriette AU - Grumach, Anete S AU - Hide, Michihiro AU - Katelaris, Constance AU - Lockey, Richard AU - Longhurst, Hilary AU - Lumry, William R. AU - Martinez-Saguer, Inmaculada AU - Moldovan, Dumitru AU - Nast, Alexander AU - Pawankar, Ruby AU - Potter, Paul AU - Riedl, Marc AU - Ritchie, Bruce AU - Rosenwasser, Lanny AU - Sánchez-Borges, Mario AU - Zhi, Yuxiang AU - Zuraw, Bruce AU - Craig, Timothy AB - Hereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and appropriate therapy are essential. This update and revision of the global guideline for HAE provides up-to-date consensus recommendations for the management of HAE. In the development of this update and revision of the guideline, an international expert panel reviewed the existing evidence and developed 20 recommendations that were discussed, finalized and consented during the guideline consensus conference in June 2016 in Vienna. The final version of this update and revision of the guideline incorporates the contributions of a board of expert reviewers and the endorsing societies. The goal of this guideline update and revision is to provide clinicians and their patients with guidance that will assist them in making rational decisions in the management of HAE with deficient C1-inhibitor (type 1) and HAE with dysfunctional C1-inhibitor (type 2). The key clinical questions covered by these recommendations are: 1) How should HAE-1/2 be defined and classified?, 2) How should HAE-1/2 be diagnosed?, 3) Should HAE-1/2 patients receive prophylactic and/or on-demand treatment and what treatment options should be used?, 4) Should HAE-1/2 management be different for special HAE-1/2 patient groups such as pregnant/lactating women or children?, and 5) Should HAE-1/2 management incorporate self-administration of therapies and patient support measures? This article is co-published with permission in Allergy and the World Allergy Organization Journal. DA - 2018-02-27 DB - OpenUCT DO - 10.1186/s40413-017-0180-1 DP - University of Cape Town J1 - World Allergy Organization Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2018 T1 - The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update TI - The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update UR - http://hdl.handle.net/11427/27926 ER - en_ZA
dc.identifier.urihttp://dx.doi.org/10.1186/s40413-017-0180-1
dc.identifier.urihttp://hdl.handle.net/11427/27926
dc.identifier.vancouvercitationMaurer M, Magerl M, Ansotegui I, Aygören-Pürsün E, Betschel S, Bork K, et al. The international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update. World Allergy Organization Journal. 2018; http://hdl.handle.net/11427/27926.en_ZA
dc.language.isoen
dc.publisherBioMed Central
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rights.holderThe Author(s).
dc.sourceWorld Allergy Organization Journal
dc.source.urihttps://waojournal.biomedcentral.com/
dc.subject.otherHereditary angioedema
dc.subject.otherC1-inhibitor
dc.subject.otherDiagnosis
dc.subject.otherTherapy
dc.subject.otherManagement
dc.subject.otherIndividualized therapy
dc.subject.otherGRADE
dc.subject.otherGuideline
dc.subject.otherProphylaxis
dc.subject.otherQuality of life
dc.subject.otherRecommendations
dc.subject.otherSelf-administration
dc.titleThe international WAO/EAACI guideline for the management of hereditary angioedema – the 2017 revision and update
dc.typeJournal Article
uct.type.filetypeText
uct.type.filetypeImage
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