Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa

dc.contributor.authorDegrendele, Céline
dc.contributor.authorProkeš, Roman
dc.contributor.authorŠenk, Petr
dc.contributor.authorJílková, Simona Rozárka
dc.contributor.authorKohoutek, Jiří
dc.contributor.authorMelymuk, Lisa
dc.contributor.authorPřibylová, Petra
dc.contributor.authorDalvie, Mohamed Aqiel
dc.contributor.authorRöösli, Martin
dc.contributor.authorKlánová, Jana
dc.contributor.authorFuhrimann, Samuel
dc.date.accessioned2023-09-18T10:04:51Z
dc.date.available2023-09-18T10:04:51Z
dc.date.issued2022-10-21
dc.date.updated2022-10-26T11:08:13Z
dc.description.abstractOver the last decades, concern has arisen worldwide about the negative impacts of pesticides on the environment and human health. Exposure via dust ingestion is important for many chemicals but poorly characterized for pesticides, particularly in Africa. We investigated the spatial and temporal variations of 30 pesticides in dust and estimated the human exposure via dust ingestion, which was compared to inhalation and soil ingestion. Indoor dust samples were collected from thirty-eight households and two schools located in two agricultural regions in South Africa and were analyzed using high-performance liquid chromatography coupled to tandem mass spectrometry. We found 10 pesticides in dust, with chlorpyrifos, terbuthylazine, carbaryl, diazinon, carbendazim, and tebuconazole quantified in >50% of the samples. Over seven days, no significant temporal variations in the dust levels of individual pesticides were found. Significant spatial variations were observed for some pesticides, highlighting the importance of proximity to agricultural fields or of indoor pesticide use. For five out of the nineteen pesticides quantified in dust, air, or soil (i.e., carbendazim, chlorpyrifos, diazinon, diuron and propiconazole), human intake via dust ingestion was important (>10%) compared to inhalation or soil ingestion. Dust ingestion should therefore be considered in future human exposure assessment to pesticides.
dc.identifierdoi: 10.3390/toxics10100629
dc.identifier.apacitationDegrendele, C., Prokeš, R., Šenk, P., Jílková, S. R., Kohoutek, J., Melymuk, L., ... Fuhrimann, S. (2022). Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa. <i>Toxics</i>, 10(10), 629. http://hdl.handle.net/11427/38720en_ZA
dc.identifier.chicagocitationDegrendele, Céline, Roman Prokeš, Petr Šenk, Simona Rozárka Jílková, Jiří Kohoutek, Lisa Melymuk, Petra Přibylová, et al "Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa." <i>Toxics</i> 10, 10. (2022): 629. http://hdl.handle.net/11427/38720en_ZA
dc.identifier.citationDegrendele, C., Prokeš, R., Šenk, P., Jílková, S.R., Kohoutek, J., Melymuk, L., Přibylová, P. & Dalvie, M.A. et al. 2022. Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa. <i>Toxics.</i> 10(10):629. http://hdl.handle.net/11427/38720en_ZA
dc.identifier.ris TY - Journal Article AU - Degrendele, Céline AU - Prokeš, Roman AU - Šenk, Petr AU - Jílková, Simona Rozárka AU - Kohoutek, Jiří AU - Melymuk, Lisa AU - Přibylová, Petra AU - Dalvie, Mohamed Aqiel AU - Röösli, Martin AU - Klánová, Jana AU - Fuhrimann, Samuel AB - Over the last decades, concern has arisen worldwide about the negative impacts of pesticides on the environment and human health. Exposure via dust ingestion is important for many chemicals but poorly characterized for pesticides, particularly in Africa. We investigated the spatial and temporal variations of 30 pesticides in dust and estimated the human exposure via dust ingestion, which was compared to inhalation and soil ingestion. Indoor dust samples were collected from thirty-eight households and two schools located in two agricultural regions in South Africa and were analyzed using high-performance liquid chromatography coupled to tandem mass spectrometry. We found 10 pesticides in dust, with chlorpyrifos, terbuthylazine, carbaryl, diazinon, carbendazim, and tebuconazole quantified in &gt;50% of the samples. Over seven days, no significant temporal variations in the dust levels of individual pesticides were found. Significant spatial variations were observed for some pesticides, highlighting the importance of proximity to agricultural fields or of indoor pesticide use. For five out of the nineteen pesticides quantified in dust, air, or soil (i.e., carbendazim, chlorpyrifos, diazinon, diuron and propiconazole), human intake via dust ingestion was important (&gt;10%) compared to inhalation or soil ingestion. Dust ingestion should therefore be considered in future human exposure assessment to pesticides. DA - 2022-10-21 DB - OpenUCT DP - University of Cape Town IS - 10 J1 - Toxics LK - https://open.uct.ac.za PY - 2022 T1 - Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa TI - Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa UR - http://hdl.handle.net/11427/38720 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/38720
dc.identifier.vancouvercitationDegrendele C, Prokeš R, Šenk P, Jílková SR, Kohoutek J, Melymuk L, et al. Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa. Toxics. 2022;10(10):629. http://hdl.handle.net/11427/38720.en_ZA
dc.publisherMultidisciplinary Digital Publishing Institute
dc.publisher.departmentFamily Medicine
dc.publisher.facultyHealth Sciences
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceToxics
dc.source.journalissue10
dc.source.journalvolume10
dc.source.pagination629
dc.source.urihttps://www.mdpi.com/journal/toxics
dc.titleHuman Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa
dc.typeJournal Article
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