The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens

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dc.contributor.advisorJaspan, Heather Ben_ZA
dc.contributor.advisorGray, Clive Men_ZA
dc.contributor.authorKidzeru, Elvis Banboyeen_ZA
dc.date.accessioned2014-07-29T09:04:15Z
dc.date.available2014-07-29T09:04:15Z
dc.date.issued2013en_ZA
dc.descriptionIncludes abstract.
dc.descriptionIncludes bibliographical references.
dc.description.abstractImmunization against vaccine-preventable infections is essential to reducing childhood morbidity and mortality. The immaturity and tolerogenicity of the immune system of infants renders them susceptible to infectious diseases and makes induction of protective immunity via vaccines a challenge. HIV-exposed infants are HIV uninfected and born to HIV-infected mothers and have increased morbidity and mortality of unknown aetiology. We hypothesise that T cells of HIV-exposed uninfected (HEU) infants have impaired proliferative ability and cytokine production in response to vaccine antigens than HIV unexposed (HU) infants.en_ZA
dc.identifier.apacitationKidzeru, E. B. (2013). <i>The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/3411en_ZA
dc.identifier.chicagocitationKidzeru, Elvis Banboye. <i>"The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2013. http://hdl.handle.net/11427/3411en_ZA
dc.identifier.citationKidzeru, E. 2013. The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Kidzeru, Elvis Banboye AB - Immunization against vaccine-preventable infections is essential to reducing childhood morbidity and mortality. The immaturity and tolerogenicity of the immune system of infants renders them susceptible to infectious diseases and makes induction of protective immunity via vaccines a challenge. HIV-exposed infants are HIV uninfected and born to HIV-infected mothers and have increased morbidity and mortality of unknown aetiology. We hypothesise that T cells of HIV-exposed uninfected (HEU) infants have impaired proliferative ability and cytokine production in response to vaccine antigens than HIV unexposed (HU) infants. DA - 2013 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens TI - The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens UR - http://hdl.handle.net/11427/3411 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3411
dc.identifier.vancouvercitationKidzeru EB. The effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigens. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2013 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3411en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherMedicineen_ZA
dc.titleThe effect of HIV-exposure on immune responses to expanded programme on immunization vaccines and antigensen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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