Cerebral granulomas: differentiating between tuberculosis and cysticercosis

dc.contributor.advisorLeary, PM
dc.contributor.authorHemingway, Cheryl
dc.date.accessioned2026-10-06T12:32:43Z
dc.date.available2026-10-06T12:32:43Z
dc.date.issued1999
dc.date.updated2026-10-06T12:24:30Z
dc.description.abstractThe study attempted to determine the optimal feasible method to differentiate the intracranial single granuloma caused by tuberculosis from that caused by cysticercosis. 62 patients who were found to have a single granuloma on computerised tomography (CT) scanning • answered a questionnaire • were examined • underwent further special investigations looking for evidence of either tuberculosis or cysticercosis. The 47 mantoux negative patients in whom a diagnosis of tuberculosis was unlikely were treated with the anti-helminthic albendazole. The remaining 15 patients, all of whom had a positive mantoux skin test, received six months of anti-tuberculosis chemotherapy. At follow-up at 3 months only 8% of children had had further seizures and the CT scan revealed that in 96% of children the lesions had disappeared or calcified. This increased to 98% at 6-month follow-up. Calcification occurred only in those diagnosed as neurocysticercosis. Analysis of special investigations performed showed that no single investigation taken in isolation is able definitively to differentiate the single granuloma caused by neurocysticercosis from that caused by tuberculosis.
dc.identifier.apacitationHemingway, C. (1999). <i>Cerebral granulomas: differentiating between tuberculosis and cysticercosis</i>. (). University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. Retrieved from http://hdl.handle.net/11427/43856en_ZA
dc.identifier.chicagocitationHemingway, Cheryl. <i>"Cerebral granulomas: differentiating between tuberculosis and cysticercosis."</i> ., University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 1999. http://hdl.handle.net/11427/43856en_ZA
dc.identifier.citationHemingway, C. 1999. Cerebral granulomas: differentiating between tuberculosis and cysticercosis. . University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health. http://hdl.handle.net/11427/43856en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Hemingway, Cheryl AB - The study attempted to determine the optimal feasible method to differentiate the intracranial single granuloma caused by tuberculosis from that caused by cysticercosis. 62 patients who were found to have a single granuloma on computerised tomography (CT) scanning • answered a questionnaire • were examined • underwent further special investigations looking for evidence of either tuberculosis or cysticercosis. The 47 mantoux negative patients in whom a diagnosis of tuberculosis was unlikely were treated with the anti-helminthic albendazole. The remaining 15 patients, all of whom had a positive mantoux skin test, received six months of anti-tuberculosis chemotherapy. At follow-up at 3 months only 8% of children had had further seizures and the CT scan revealed that in 96% of children the lesions had disappeared or calcified. This increased to 98% at 6-month follow-up. Calcification occurred only in those diagnosed as neurocysticercosis. Analysis of special investigations performed showed that no single investigation taken in isolation is able definitively to differentiate the single granuloma caused by neurocysticercosis from that caused by tuberculosis. DA - 1999 DB - OpenUCT DP - University of Cape Town KW - tuberculosis KW - cysticercosis LK - https://open.uct.ac.za PB - University of Cape Town PY - 1999 T1 - Cerebral granulomas: differentiating between tuberculosis and cysticercosis TI - Cerebral granulomas: differentiating between tuberculosis and cysticercosis UR - http://hdl.handle.net/11427/43856 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/43856
dc.identifier.vancouvercitationHemingway C. Cerebral granulomas: differentiating between tuberculosis and cysticercosis. []. University of Cape Town ,Faculty of Health Sciences ,Department of Paediatrics and Child Health, 1999 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/43856en_ZA
dc.language.isoen
dc.language.rfc3066eng
dc.publisher.departmentDepartment of Paediatrics and Child Health
dc.publisher.facultyFaculty of Health Sciences
dc.publisher.institutionUniversity of Cape Town
dc.subjecttuberculosis
dc.subjectcysticercosis
dc.titleCerebral granulomas: differentiating between tuberculosis and cysticercosis
dc.typeThesis / Dissertation
dc.type.qualificationlevelMasters
dc.type.qualificationlevelMMed
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