An exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africa

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dc.contributor.advisorJohn-Langba, Johannesen_ZA
dc.contributor.authorNandudu, Norahen_ZA
dc.date.accessioned2015-09-15T10:11:50Z
dc.date.available2015-09-15T10:11:50Z
dc.date.issued2013en_ZA
dc.description.abstractHIV and AIDS has severely inflicted suffering on the global population and reported to be the worst killer disease in sub-Saharan Africa. Preventive measures such as condom use among young people is still low and less effective in preventing the spread of the disease, it was recommended by the United Nations General Assembly Special Session on HIV and AIDS (2001) to accelerate the development of HIV vaccine aimed at curbing the disease. This study sought to explore young women’s experiences and perceptions about HIV prevention vaccine clinical trials so as to inform the design and implementation of vaccine trials in Africa. The study employed purposive sampling to interview 27 participants using semi-structured interview schedule. A tape recorder was used to capture data and coding procedures were used to analyze data. Findings drawn from participants’ responses and compared with literature from previous studies on vaccine trials and social development theories indicate that participants decide to join HIV prevention vaccine clinical trials because they hope to be protected from HIV infection. Most importantly participants hope to get access to medical care and treatment, meanwhile some participants perceived HIV vaccines harmful to humans hence they usually decline to participate. The study also identified study participation challenges related to socio-cultural and historical aspects. Although vaccines have had some success stories in the prevention and control of infectious diseases such as the eradication of polio, smallpox and measles, prevailing challenges need to be addressed if vaccine development is to be feasible. Providing more information, reinforcement of community awareness and mobilization around issues of HIV vaccine clinical trials at all levels of vaccine design and implementation is required to ensure appropriateness and acceptability of vaccine trial participation.en_ZA
dc.identifier.apacitationNandudu, N. (2013). <i>An exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africa</i>. (Thesis). University of Cape Town ,Faculty of Humanities ,Department of Social Development. Retrieved from http://hdl.handle.net/11427/13950en_ZA
dc.identifier.chicagocitationNandudu, Norah. <i>"An exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africa."</i> Thesis., University of Cape Town ,Faculty of Humanities ,Department of Social Development, 2013. http://hdl.handle.net/11427/13950en_ZA
dc.identifier.citationNandudu, N. 2013. An exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africa. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Nandudu, Norah AB - HIV and AIDS has severely inflicted suffering on the global population and reported to be the worst killer disease in sub-Saharan Africa. Preventive measures such as condom use among young people is still low and less effective in preventing the spread of the disease, it was recommended by the United Nations General Assembly Special Session on HIV and AIDS (2001) to accelerate the development of HIV vaccine aimed at curbing the disease. This study sought to explore young women’s experiences and perceptions about HIV prevention vaccine clinical trials so as to inform the design and implementation of vaccine trials in Africa. The study employed purposive sampling to interview 27 participants using semi-structured interview schedule. A tape recorder was used to capture data and coding procedures were used to analyze data. Findings drawn from participants’ responses and compared with literature from previous studies on vaccine trials and social development theories indicate that participants decide to join HIV prevention vaccine clinical trials because they hope to be protected from HIV infection. Most importantly participants hope to get access to medical care and treatment, meanwhile some participants perceived HIV vaccines harmful to humans hence they usually decline to participate. The study also identified study participation challenges related to socio-cultural and historical aspects. Although vaccines have had some success stories in the prevention and control of infectious diseases such as the eradication of polio, smallpox and measles, prevailing challenges need to be addressed if vaccine development is to be feasible. Providing more information, reinforcement of community awareness and mobilization around issues of HIV vaccine clinical trials at all levels of vaccine design and implementation is required to ensure appropriateness and acceptability of vaccine trial participation. DA - 2013 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 T1 - An exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africa TI - An exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africa UR - http://hdl.handle.net/11427/13950 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/13950
dc.identifier.vancouvercitationNandudu N. An exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africa. [Thesis]. University of Cape Town ,Faculty of Humanities ,Department of Social Development, 2013 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/13950en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Social Developmenten_ZA
dc.publisher.facultyFaculty of Humanitiesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherSocial Developmenten_ZA
dc.titleAn exploration of young women's perceptions and experiences of participating in HIV prevention vaccine clinical trials in Nyanga Township in the Western Cape, South Africaen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMSocScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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