Dyspnoea: Pathophysiology and a clinical approach

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dc.contributor.authorCoccia, Cecilia B I
dc.contributor.authorPalkowski, Gregori H
dc.contributor.authorSchweitzer, Beverley
dc.contributor.authorMotsohi, Tshepo
dc.contributor.authorNtusi, Ntobeko
dc.date.accessioned2021-10-08T07:20:31Z
dc.date.available2021-10-08T07:20:31Z
dc.date.issued2015
dc.description.abstractDyspnoea, also known as shortness of breath or breathlessness, is a subjective awareness of the sensation of uncomfortable breathing. It may be of physiological, pathological or social origin. The pathophysiology of dyspnoea is complex, and involves the activation of several pathways that lead to increased work of breathing, stimulation of the receptors of the upper or lower airway, lung parenchyma, or chest wall, and excessive stimulation of the respiratory centre by central and peripheral chemoreceptors. Activation of these pathways is relayed to the central nervous system via respiratory muscle and vagal afferents, which are consequently interpreted by the individual in the context of the affective state, attention, and prior experience, resulting in the awareness of breathing. The clinical evaluation and approach to the management of dyspnoea are directed by the clinical presentation and underlying cause. The causes of dyspnoea are manifold, and include a spectrum of disorders, from benign to serious and life-threatening entities. The pathophysiology, aetiology, clinical presentation and management of dyspnoea are reviewed.
dc.identifier.apacitationCoccia, C. B. I., Palkowski, G. H., Schweitzer, B., Motsohi, T., & Ntusi, N. (2015). Dyspnoea: Pathophysiology and a clinical approach. <i>South African Medical Journal</i>, 106(1), 32 - 177. http://hdl.handle.net/11427/34942en_ZA
dc.identifier.chicagocitationCoccia, Cecilia B I, Gregori H Palkowski, Beverley Schweitzer, Tshepo Motsohi, and Ntobeko Ntusi "Dyspnoea: Pathophysiology and a clinical approach." <i>South African Medical Journal</i> 106, 1. (2015): 32 - 177. http://hdl.handle.net/11427/34942en_ZA
dc.identifier.citationCoccia, C.B.I., Palkowski, G.H., Schweitzer, B., Motsohi, T. & Ntusi, N. 2015. Dyspnoea: Pathophysiology and a clinical approach. <i>South African Medical Journal.</i> 106(1):32 - 177. http://hdl.handle.net/11427/34942en_ZA
dc.identifier.issn0038-2469
dc.identifier.ris TY - Journal Article AU - Coccia, Cecilia B I AU - Palkowski, Gregori H AU - Schweitzer, Beverley AU - Motsohi, Tshepo AU - Ntusi, Ntobeko AB - Dyspnoea, also known as shortness of breath or breathlessness, is a subjective awareness of the sensation of uncomfortable breathing. It may be of physiological, pathological or social origin. The pathophysiology of dyspnoea is complex, and involves the activation of several pathways that lead to increased work of breathing, stimulation of the receptors of the upper or lower airway, lung parenchyma, or chest wall, and excessive stimulation of the respiratory centre by central and peripheral chemoreceptors. Activation of these pathways is relayed to the central nervous system via respiratory muscle and vagal afferents, which are consequently interpreted by the individual in the context of the affective state, attention, and prior experience, resulting in the awareness of breathing. The clinical evaluation and approach to the management of dyspnoea are directed by the clinical presentation and underlying cause. The causes of dyspnoea are manifold, and include a spectrum of disorders, from benign to serious and life-threatening entities. The pathophysiology, aetiology, clinical presentation and management of dyspnoea are reviewed. DA - 2015 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - South African Medical Journal LK - https://open.uct.ac.za PY - 2015 SM - 0038-2469 T1 - Dyspnoea: Pathophysiology and a clinical approach TI - Dyspnoea: Pathophysiology and a clinical approach UR - http://hdl.handle.net/11427/34942 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34942
dc.identifier.vancouvercitationCoccia CBI, Palkowski GH, Schweitzer B, Motsohi T, Ntusi N. Dyspnoea: Pathophysiology and a clinical approach. South African Medical Journal. 2015;106(1):32 - 177. http://hdl.handle.net/11427/34942.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Public Health and Family Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceSouth African Medical Journal
dc.source.journalissue1
dc.source.journalvolume106
dc.source.pagination32 - 177
dc.source.urihttps://dx.doi.org/10.7196/SAMJ.2016.v106i1.10324
dc.subject.otherDyspnoea
dc.subject.otherBreathlessness
dc.subject.otherShortness of breath
dc.subject.otherHeart failure
dc.subject.otherAfrica
dc.titleDyspnoea: Pathophysiology and a clinical approach
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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