Warfarin in non-valvular atrial fibrillation

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dc.contributor.authorDalby, Anthony J
dc.contributor.authorWessels, Pieter
dc.contributor.authorOpie, Lionel H
dc.date.accessioned2021-10-08T07:20:26Z
dc.date.available2021-10-08T07:20:26Z
dc.date.issued2013
dc.description.abstractThe development of novel oral anticoagulants that are effective alternatives to warfarin in non-valvular atrial fibrillation (AF) is a welcome advance. However, a variety of unresolved problems with their use, and not least with their cost, make it important to re-evaluate the use of warfarin as it will likely remain the anticoagulant of choice in South African patients with non-valvular AF for the foreseeable future. In this article, we review the correct clinical use of warfarin. Guidance is provided on commencing warfarin treatment, maintenance dosing, the recommended steps when temporary withdrawal of treatment is necessary, the management of bleeding, and the use of warfarin in chronic kidney disease. Techniques for changing from warfarin to one of the new oral anticoagulants and vice versa are included.
dc.identifier.apacitationDalby, A. J., Wessels, P., & Opie, L. H. (2013). Warfarin in non-valvular atrial fibrillation. <i>South African Medical Journal</i>, 103(12), 901 - 177. http://hdl.handle.net/11427/34916en_ZA
dc.identifier.chicagocitationDalby, Anthony J, Pieter Wessels, and Lionel H Opie "Warfarin in non-valvular atrial fibrillation." <i>South African Medical Journal</i> 103, 12. (2013): 901 - 177. http://hdl.handle.net/11427/34916en_ZA
dc.identifier.citationDalby, A.J., Wessels, P. & Opie, L.H. 2013. Warfarin in non-valvular atrial fibrillation. <i>South African Medical Journal.</i> 103(12):901 - 177. http://hdl.handle.net/11427/34916en_ZA
dc.identifier.issn0038-2469
dc.identifier.ris TY - Journal Article AU - Dalby, Anthony J AU - Wessels, Pieter AU - Opie, Lionel H AB - The development of novel oral anticoagulants that are effective alternatives to warfarin in non-valvular atrial fibrillation (AF) is a welcome advance. However, a variety of unresolved problems with their use, and not least with their cost, make it important to re-evaluate the use of warfarin as it will likely remain the anticoagulant of choice in South African patients with non-valvular AF for the foreseeable future. In this article, we review the correct clinical use of warfarin. Guidance is provided on commencing warfarin treatment, maintenance dosing, the recommended steps when temporary withdrawal of treatment is necessary, the management of bleeding, and the use of warfarin in chronic kidney disease. Techniques for changing from warfarin to one of the new oral anticoagulants and vice versa are included. DA - 2013 DB - OpenUCT DP - University of Cape Town IS - 12 J1 - South African Medical Journal LK - https://open.uct.ac.za PY - 2013 SM - 0038-2469 T1 - Warfarin in non-valvular atrial fibrillation TI - Warfarin in non-valvular atrial fibrillation UR - http://hdl.handle.net/11427/34916 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34916
dc.identifier.vancouvercitationDalby AJ, Wessels P, Opie LH. Warfarin in non-valvular atrial fibrillation. South African Medical Journal. 2013;103(12):901 - 177. http://hdl.handle.net/11427/34916.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Cardiology
dc.publisher.facultyFaculty of Health Sciences
dc.sourceSouth African Medical Journal
dc.source.journalissue12
dc.source.journalvolume103
dc.source.pagination901 - 177
dc.source.urihttps://dx.doi.org/10.7196/SAMJ.7172
dc.subject.otherAdministration, Oral
dc.subject.otherAnticoagulants
dc.subject.otherAtrial Fibrillation
dc.subject.otherDose-Response Relationship, Drug
dc.subject.otherDrug Interactions
dc.subject.otherDrug Monitoring
dc.subject.otherHemorrhage
dc.subject.otherHumans
dc.subject.otherMedication Therapy Management
dc.subject.otherPractice Guidelines as Topic
dc.subject.otherStroke
dc.subject.otherWarfarin
dc.titleWarfarin in non-valvular atrial fibrillation
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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