Receptor simulation and the shape of the concentration-response curve and its congeners

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dc.contributor.authorCridland, J.S.
dc.contributor.authorWitten, G.Q.
dc.date.accessioned2016-01-04T14:01:36Z
dc.date.available2016-01-04T14:01:36Z
dc.date.issued2003
dc.date.updated2016-01-04T13:39:54Z
dc.description.abstractWe have investigated the utility of curves used to represent concentration (or dose) plotted against response (or effect). We applied crude survival data from our laboratory to demonstrate that a known hyperbolic curve compares favourably with the conventionally used sigmoidal regression in robustness, while avoiding problems associated with the use of transforms.en_ZA
dc.identifier.apacitationCridland, J. S., & Witten, G. Q. (2003). Receptor simulation and the shape of the concentration-response curve and its congeners. <i>South African Journal of Science</i>, http://hdl.handle.net/11427/16201en_ZA
dc.identifier.chicagocitationCridland, J.S., and G.Q. Witten "Receptor simulation and the shape of the concentration-response curve and its congeners." <i>South African Journal of Science</i> (2003) http://hdl.handle.net/11427/16201en_ZA
dc.identifier.citationCridland, J. S., & Witten, G. (2003). Receptor simulation and the shape of the concentration-response curve and its congeners: News and views. South African Journal of Science, 99 (7&8), p. 302-303.en_ZA
dc.identifier.issn0038-2353en_ZA
dc.identifier.ris TY - Journal Article AU - Cridland, J.S. AU - Witten, G.Q. AB - We have investigated the utility of curves used to represent concentration (or dose) plotted against response (or effect). We applied crude survival data from our laboratory to demonstrate that a known hyperbolic curve compares favourably with the conventionally used sigmoidal regression in robustness, while avoiding problems associated with the use of transforms. DA - 2003 DB - OpenUCT DP - University of Cape Town J1 - South African Journal of Science LK - https://open.uct.ac.za PB - University of Cape Town PY - 2003 SM - 0038-2353 T1 - Receptor simulation and the shape of the concentration-response curve and its congeners TI - Receptor simulation and the shape of the concentration-response curve and its congeners UR - http://hdl.handle.net/11427/16201 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/16201
dc.identifier.vancouvercitationCridland JS, Witten GQ. Receptor simulation and the shape of the concentration-response curve and its congeners. South African Journal of Science. 2003; http://hdl.handle.net/11427/16201.en_ZA
dc.languageengen_ZA
dc.publisherAcademy of Science of South Africa (ASSAf)en_ZA
dc.publisher.departmentDivision of Clinical Pharmacologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsCreative Commons Attribution 4.0 International (CC BY 4.0)*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_ZA
dc.sourceSouth African Journal of Scienceen_ZA
dc.source.urihttp://www.sajs.co.za/
dc.titleReceptor simulation and the shape of the concentration-response curve and its congenersen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetype
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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