The development of computational biology in South Africa: successes achieved and lessons learnt

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dc.contributor.authorMulder, Nicola Jen_ZA
dc.contributor.authorChristoffels, Alanen_ZA
dc.contributor.authorDe Oliveira, Tulioen_ZA
dc.contributor.authorGamieldien, Junaiden_ZA
dc.contributor.authorHazelhurst, Scotten_ZA
dc.contributor.authorJoubert, Fourieen_ZA
dc.contributor.authorKumuthini, Juditen_ZA
dc.contributor.authorPillay, Ché Sen_ZA
dc.contributor.authorSnoep, Jacky Len_ZA
dc.contributor.authorBishop, Özlem Tastanen_ZA
dc.contributor.authorTiffin, Nickien_ZA
dc.date.accessioned2016-02-10T14:46:28Z
dc.date.available2016-02-10T14:46:28Z
dc.date.issued2016en_ZA
dc.description.abstractBioinformatics is now a critical skill in many research and commercial environments as biological data are increasing in both size and complexity. South African researchers recognized this need in the mid-1990s and responded by working with the government as well as international bodies to develop initiatives to build bioinformatics capacity in the country. Significant injections of support from these bodies provided a springboard for the establishment of computational biology units at multiple universities throughout the country, which took on teaching, basic research and support roles. Several challenges were encountered, for example with unreliability of funding, lack of skills, and lack of infrastructure. However, the bioinformatics community worked together to overcome these, and South Africa is now arguably the leading country in bioinformatics on the African continent. Here we discuss how the discipline developed in the country, highlighting the challenges, successes, and lessons learnt.en_ZA
dc.identifier.apacitationMulder, N. J., Christoffels, A., De Oliveira, T., Gamieldien, J., Hazelhurst, S., Joubert, F., ... Tiffin, N. (2016). The development of computational biology in South Africa: successes achieved and lessons learnt. <i>PLOS Computational Biology</i>, http://hdl.handle.net/11427/16947en_ZA
dc.identifier.chicagocitationMulder, Nicola J, Alan Christoffels, Tulio De Oliveira, Junaid Gamieldien, Scott Hazelhurst, Fourie Joubert, Judit Kumuthini, et al "The development of computational biology in South Africa: successes achieved and lessons learnt." <i>PLOS Computational Biology</i> (2016) http://hdl.handle.net/11427/16947en_ZA
dc.identifier.citationdoi:10.1371/journal.pcbi.1004395en_ZA
dc.identifier.ris TY - Journal Article AU - Mulder, Nicola J AU - Christoffels, Alan AU - De Oliveira, Tulio AU - Gamieldien, Junaid AU - Hazelhurst, Scott AU - Joubert, Fourie AU - Kumuthini, Judit AU - Pillay, Ché S AU - Snoep, Jacky L AU - Bishop, Özlem Tastan AU - Tiffin, Nicki AB - Bioinformatics is now a critical skill in many research and commercial environments as biological data are increasing in both size and complexity. South African researchers recognized this need in the mid-1990s and responded by working with the government as well as international bodies to develop initiatives to build bioinformatics capacity in the country. Significant injections of support from these bodies provided a springboard for the establishment of computational biology units at multiple universities throughout the country, which took on teaching, basic research and support roles. Several challenges were encountered, for example with unreliability of funding, lack of skills, and lack of infrastructure. However, the bioinformatics community worked together to overcome these, and South Africa is now arguably the leading country in bioinformatics on the African continent. Here we discuss how the discipline developed in the country, highlighting the challenges, successes, and lessons learnt. DA - 2016 DB - OpenUCT DO - 10.1371/journal.pcbi.1004395 DP - University of Cape Town J1 - PLOS Computational Biology LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - The development of computational biology in South Africa: successes achieved and lessons learnt TI - The development of computational biology in South Africa: successes achieved and lessons learnt UR - http://hdl.handle.net/11427/16947 ER - en_ZA
dc.identifier.urihttp://dx.doi.org/10.1371/journal.pcbi.1004395en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/16947
dc.identifier.vancouvercitationMulder NJ, Christoffels A, De Oliveira T, Gamieldien J, Hazelhurst S, Joubert F, et al. The development of computational biology in South Africa: successes achieved and lessons learnt. PLOS Computational Biology. 2016; http://hdl.handle.net/11427/16947.en_ZA
dc.language.isoengen_ZA
dc.publisherPublic Library of Scienceen_ZA
dc.publisher.departmentInstitute of Infectious Disease and Molecular Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_ZA
dc.rights.holder© 2016 Mulder et alen_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/4.0en_ZA
dc.sourcePLOS Computational Biologyen_ZA
dc.source.urihttp://journals.plos.org/ploscompbiolen_ZA
dc.subject.otherBioinformaticsen_ZA
dc.subject.otherSouth Africaen_ZA
dc.subject.otherGenomic databasesen_ZA
dc.subject.otherComputational biologyen_ZA
dc.subject.otherGenome analysisen_ZA
dc.subject.otherGenomicsen_ZA
dc.subject.otherHealth services researchen_ZA
dc.subject.otherResearch grantsen_ZA
dc.titleThe development of computational biology in South Africa: successes achieved and lessons learnten_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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