Symptomatic developmental venous anomalies

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dc.contributor.advisorLe Feuvre, David Edmond Johnen_ZA
dc.contributor.advisorTaylor, Allanen_ZA
dc.contributor.authorBen Husien, Mohammeden_ZA
dc.date.accessioned2016-07-21T11:01:44Z
dc.date.available2016-07-21T11:01:44Z
dc.date.issued2016en_ZA
dc.description.abstractDevelopmental Venous Anomalies are a normal variant that may be associated with other cerebral vascular malformation. They have bean previously referred to Venous angiomas. DVAs are the most frequently encountered cerebral vascular malformation and their incidence is reported to be high as2.6%. DVAs are classified into two types based on draining veins. Either deep or superficial. Those that drain into sub-ependymal veins are classified as deep and those that drain into cortical pial veins are classified as superficial. The trans-cerebral veins join either the deep or superficial venous systems by crossing a varying length of the brain parenchyma. Controversy surrounds their exact clinical significance, as DVAs are rarely symptomatic. The symptoms displayed by a patient can be related to a lesion that is associated with DVAs, such as a cavernoma. To describe the patients presenting to a single unit over a 10-year period with symptoms attributable to aDVA. Out of 19 patients in the database with the diagnosis of DVA, 10 were identified where the clinical presentation was directly related to the DVA. Seven of the patients presented with haemorrhage, 6 had parenchymal bleeds and one was intraventricular. Two patients had neurological deficit, 1 was transient and one was progressive. One patient had sudden severe headache with no evidence of haemorrhage on CT scan. The age range was from 14 to 55 with a mean of 32,7 years. Four patients were male and 6 were female. Of the patients that presented with haemorrhage only one had a fistula, three other patients with haemorrhage had evidence on DSA of stenosis of the large collector vein, In the remaining 3 patients no reason for the bleed could be detected. One patient presented with left hemianopia that resolved after several hours, DSA showed minimal caput medusa with delayed filling of the collector vein. The other patient that presented with progressive neurological deficit in the form of progressive leg spasticity and dysarthria, Angiography showed a large collecting vein that drains in the jugular bulb was stenosed. The last patient that presented with sudden severe headaches, with no haemorrhage identified on CT scan, On DSA there was early filling of the DVA veins compared to other cerebral veins and two prominent posterior communicating thalamoperforating vessels were seen.en_ZA
dc.identifier.apacitationBen Husien, M. (2016). <i>Symptomatic developmental venous anomalies</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Neurosurgery. Retrieved from http://hdl.handle.net/11427/20556en_ZA
dc.identifier.chicagocitationBen Husien, Mohammed. <i>"Symptomatic developmental venous anomalies."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Neurosurgery, 2016. http://hdl.handle.net/11427/20556en_ZA
dc.identifier.citationBen Husien, M. 2016. Symptomatic developmental venous anomalies. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Ben Husien, Mohammed AB - Developmental Venous Anomalies are a normal variant that may be associated with other cerebral vascular malformation. They have bean previously referred to Venous angiomas. DVAs are the most frequently encountered cerebral vascular malformation and their incidence is reported to be high as2.6%. DVAs are classified into two types based on draining veins. Either deep or superficial. Those that drain into sub-ependymal veins are classified as deep and those that drain into cortical pial veins are classified as superficial. The trans-cerebral veins join either the deep or superficial venous systems by crossing a varying length of the brain parenchyma. Controversy surrounds their exact clinical significance, as DVAs are rarely symptomatic. The symptoms displayed by a patient can be related to a lesion that is associated with DVAs, such as a cavernoma. To describe the patients presenting to a single unit over a 10-year period with symptoms attributable to aDVA. Out of 19 patients in the database with the diagnosis of DVA, 10 were identified where the clinical presentation was directly related to the DVA. Seven of the patients presented with haemorrhage, 6 had parenchymal bleeds and one was intraventricular. Two patients had neurological deficit, 1 was transient and one was progressive. One patient had sudden severe headache with no evidence of haemorrhage on CT scan. The age range was from 14 to 55 with a mean of 32,7 years. Four patients were male and 6 were female. Of the patients that presented with haemorrhage only one had a fistula, three other patients with haemorrhage had evidence on DSA of stenosis of the large collector vein, In the remaining 3 patients no reason for the bleed could be detected. One patient presented with left hemianopia that resolved after several hours, DSA showed minimal caput medusa with delayed filling of the collector vein. The other patient that presented with progressive neurological deficit in the form of progressive leg spasticity and dysarthria, Angiography showed a large collecting vein that drains in the jugular bulb was stenosed. The last patient that presented with sudden severe headaches, with no haemorrhage identified on CT scan, On DSA there was early filling of the DVA veins compared to other cerebral veins and two prominent posterior communicating thalamoperforating vessels were seen. DA - 2016 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - Symptomatic developmental venous anomalies TI - Symptomatic developmental venous anomalies UR - http://hdl.handle.net/11427/20556 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/20556
dc.identifier.vancouvercitationBen Husien M. Symptomatic developmental venous anomalies. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Neurosurgery, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/20556en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Neurosurgeryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherNeurosurgeryen_ZA
dc.titleSymptomatic developmental venous anomaliesen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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