MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis

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dc.contributor.authorScriven, J
dc.contributor.authorCirota, J
dc.contributor.authorViljoen, C
dc.contributor.authorBlack, M
dc.contributor.authorMeintjes, G
dc.date.accessioned2021-10-08T07:17:49Z
dc.date.available2021-10-08T07:17:49Z
dc.date.issued2013
dc.description.abstractIntravenous amphotericin B is a key component of the antifungal therapy for cryptococcal meningitis recommended in South African and international guidelines. Unfortunately, its use is associated with significant toxicity including deterioration in renal function, electrolyte disturbance, anaemia and infusion reactions. Chemical phlebitis is common following administration via peripheral cannulae. This can be complicated by bacterial infection, resulting in localised cellulitis or bacterial sepsis. Here we describe two patients with cryptococcal meningitis who developed methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia during, or shortly after treatment with amphotericin B. These cases illustrate the dangers of line-related sepsis in hospitalised individuals and some of the difficulties encountered during treatment of this condition.
dc.identifier.apacitationScriven, J., Cirota, J., Viljoen, C., Black, M., & Meintjes, G. (2013). MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis. <i>Southern African Journal of Hiv Medicine</i>, 14(3), 144 - 177. http://hdl.handle.net/11427/34826en_ZA
dc.identifier.chicagocitationScriven, J, J Cirota, C Viljoen, M Black, and G Meintjes "MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis." <i>Southern African Journal of Hiv Medicine</i> 14, 3. (2013): 144 - 177. http://hdl.handle.net/11427/34826en_ZA
dc.identifier.citationScriven, J., Cirota, J., Viljoen, C., Black, M. & Meintjes, G. 2013. MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis. <i>Southern African Journal of Hiv Medicine.</i> 14(3):144 - 177. http://hdl.handle.net/11427/34826en_ZA
dc.identifier.issn1608-9693
dc.identifier.issn2078-6751
dc.identifier.ris TY - Journal Article AU - Scriven, J AU - Cirota, J AU - Viljoen, C AU - Black, M AU - Meintjes, G AB - Intravenous amphotericin B is a key component of the antifungal therapy for cryptococcal meningitis recommended in South African and international guidelines. Unfortunately, its use is associated with significant toxicity including deterioration in renal function, electrolyte disturbance, anaemia and infusion reactions. Chemical phlebitis is common following administration via peripheral cannulae. This can be complicated by bacterial infection, resulting in localised cellulitis or bacterial sepsis. Here we describe two patients with cryptococcal meningitis who developed methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia during, or shortly after treatment with amphotericin B. These cases illustrate the dangers of line-related sepsis in hospitalised individuals and some of the difficulties encountered during treatment of this condition. DA - 2013 DB - OpenUCT DP - University of Cape Town IS - 3 J1 - Southern African Journal of Hiv Medicine LK - https://open.uct.ac.za PY - 2013 SM - 1608-9693 SM - 2078-6751 T1 - MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis TI - MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis UR - http://hdl.handle.net/11427/34826 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34826
dc.identifier.vancouvercitationScriven J, Cirota J, Viljoen C, Black M, Meintjes G. MRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis. Southern African Journal of Hiv Medicine. 2013;14(3):144 - 177. http://hdl.handle.net/11427/34826.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceSouthern African Journal of Hiv Medicine
dc.source.journalissue3
dc.source.journalvolume14
dc.source.pagination144 - 177
dc.source.urihttps://dx.doi.org/10.4102/sajhivmed.v14i3.70
dc.subject.otherMRSA
dc.subject.otherStaphylococcus
dc.subject.otheramphotericin B
dc.subject.othercryptococcal meningitis
dc.subject.otherPublic aspects of medicine
dc.subject.otherRA1-1270
dc.subject.otherMRSA
dc.subject.otherStaphylococcus
dc.subject.otheramphotericin B
dc.subject.othercryptococcal meningitis
dc.titleMRSA bacteraemia complicating amphotericin B treatment of cryptococcal meningitis
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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