Predictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study

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dc.contributor.authorKatoto, Patrick D M C
dc.contributor.authorParker, Saahier
dc.contributor.authorCoulson, Nancy
dc.contributor.authorPillay, Nirvana
dc.contributor.authorCooper, Sara
dc.contributor.authorJaca, Anelisa
dc.contributor.authorMavundza, Edison
dc.contributor.authorHouston, Gregory
dc.contributor.authorGroenewald, Candice
dc.contributor.authorEssack, Zaynab
dc.contributor.authorSimmonds, Jane
dc.contributor.authorShandu, Londiwe Deborah
dc.contributor.authorCouch, Marilyn
dc.contributor.authorKhuzwayo, Nonkululeko
dc.contributor.authorNcube, Nobukhosi
dc.contributor.authorBhengu, Phelele
dc.contributor.authorRooyen, Heidi van
dc.contributor.authorWiysonge, Charles Shey
dc.date.accessioned2022-04-13T09:30:47Z
dc.date.available2022-04-13T09:30:47Z
dc.date.issued2022-02-25
dc.date.updated2022-03-24T14:47:19Z
dc.description.abstractSouth Africa launched a mass COVID-19 vaccination campaign in May 2021, targeting 40 million adults. Understanding predictors of COVID-19 vaccine intentions was required to achieve this goal. We conducted a population-based survey in June–July 2021 using the WHO Behavioral and Social Drivers (BeSD) of COVID-19 Vaccination tool to determine predictors of vaccine hesitancy, defined as intention to refuse or uncertainty whether to accept COVID-19 vaccination. There were 1193 participants, mean age 39 (standard deviation 15) years, and 53% women, of whom 58% trusted information provided by healthcare workers and 32% were vaccine hesitant. Independent predictors of vaccine hesitancy included concerns about side effects (odds ratio (OR) 11.41; 95% confidence interval (CI) 3.5–50.80), lack of access to the online vaccine registration platform (OR 4.75; CI 2.15–10.37), distrust of government (OR 3.0; CI 1.33–6.77), belief in conspiracy theories (OR 3.01; CI 1.32–6.77), having no monthly income (OR 1.84; CI 1.12–3.07), and depending on someone else to make vaccination decision (OR 2.47; CI 1.06–5.77). We identified modifiable predictors of vaccine hesitancy at the start of South Africa’s COVID-19 vaccination rollout. These factors should be addressed by different stakeholders involved in the national immunization program through tailored communication and other effective strategies that increase vaccine literacy, reach low-income households, and engender confidence in government.
dc.identifierdoi: 10.3390/vaccines10030353
dc.identifier.apacitationKatoto, P. D. M. C., Parker, S., Coulson, N., Pillay, N., Cooper, S., Jaca, A., ... Wiysonge, C. S. (2022). Predictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study. http://hdl.handle.net/11427/36365en_ZA
dc.identifier.chicagocitationKatoto, Patrick D M C, Saahier Parker, Nancy Coulson, Nirvana Pillay, Sara Cooper, Anelisa Jaca, Edison Mavundza, et al "Predictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study." (2022) http://hdl.handle.net/11427/36365en_ZA
dc.identifier.citationVaccines 10 (3): 353 (2022)
dc.identifier.ris TY - Journal Article AU - Katoto, Patrick D M C AU - Parker, Saahier AU - Coulson, Nancy AU - Pillay, Nirvana AU - Cooper, Sara AU - Jaca, Anelisa AU - Mavundza, Edison AU - Houston, Gregory AU - Groenewald, Candice AU - Essack, Zaynab AU - Simmonds, Jane AU - Shandu, Londiwe Deborah AU - Couch, Marilyn AU - Khuzwayo, Nonkululeko AU - Ncube, Nobukhosi AU - Bhengu, Phelele AU - Rooyen, Heidi van AU - Wiysonge, Charles Shey AB - South Africa launched a mass COVID-19 vaccination campaign in May 2021, targeting 40 million adults. Understanding predictors of COVID-19 vaccine intentions was required to achieve this goal. We conducted a population-based survey in June–July 2021 using the WHO Behavioral and Social Drivers (BeSD) of COVID-19 Vaccination tool to determine predictors of vaccine hesitancy, defined as intention to refuse or uncertainty whether to accept COVID-19 vaccination. There were 1193 participants, mean age 39 (standard deviation 15) years, and 53% women, of whom 58% trusted information provided by healthcare workers and 32% were vaccine hesitant. Independent predictors of vaccine hesitancy included concerns about side effects (odds ratio (OR) 11.41; 95% confidence interval (CI) 3.5–50.80), lack of access to the online vaccine registration platform (OR 4.75; CI 2.15–10.37), distrust of government (OR 3.0; CI 1.33–6.77), belief in conspiracy theories (OR 3.01; CI 1.32–6.77), having no monthly income (OR 1.84; CI 1.12–3.07), and depending on someone else to make vaccination decision (OR 2.47; CI 1.06–5.77). We identified modifiable predictors of vaccine hesitancy at the start of South Africa’s COVID-19 vaccination rollout. These factors should be addressed by different stakeholders involved in the national immunization program through tailored communication and other effective strategies that increase vaccine literacy, reach low-income households, and engender confidence in government. DA - 2022-02-25 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PY - 2022 T1 - Predictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study TI - Predictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study UR - http://hdl.handle.net/11427/36365 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/36365
dc.identifier.urihttps://doi.org/10.3390/vaccines10030353
dc.identifier.vancouvercitationKatoto PDMC, Parker S, Coulson N, Pillay N, Cooper S, Jaca A, et al. Predictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study. 2022; http://hdl.handle.net/11427/36365.en_ZA
dc.publisherMultidisciplinary Digital Publishing Institute
dc.rights.licensehttps://creativecommons.org/licenses/by/4.0/
dc.rights.licensehttp://creativecommons.org/licenses/by/4.0/
dc.sourceVaccines
dc.source.journalissue3
dc.source.journalvolume10
dc.source.urihttps://www.mdpi.com/journal/vaccines
dc.subjectimmunization
dc.subjectvaccine acceptance
dc.subjectbehaviors
dc.subjectsocial drivers
dc.subjectSARS-CoV-2
dc.titlePredictors of COVID-19 Vaccine Hesitancy in South African Local Communities: The VaxScenes Study
dc.typeJournal Article
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