Risk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centre

dc.contributor.advisorKloppers, Jacobus
dc.contributor.authorBooyse, Karien
dc.date.accessioned2023-06-27T12:45:04Z
dc.date.available2023-06-27T12:45:04Z
dc.date.issued2023
dc.date.updated2023-06-27T12:42:00Z
dc.description.abstractBackground: Laparoscopic subtotal cholecystectomy (LSC) is utilized as a safe and feasible alternative for difficult cholecystectomies to avoid bile duct injury and can aid in avoiding conversion to open surgery. This study assesses the risk factors and outcomes of patients who underwent LSC. Methods: A retrospective analysis was conducted of patients undergoing LSC from September 2019 to August 2021. Relative clinical and operative factors as well as postoperative outcomes were analysed. Results: There were 631 consecutive cholecystectomies included, 53 of which required LSC. Nine (16.9%) used the reconstituting technique and 43 (81.8%) were fenestrating LSC, one procedure not specified. High BMI (26.4%) and previous endoscopic retrograde cholangiopancreatography (ERCP) (18.9%) were the most common indicators for expected difficulty. Severe inflammation (58.5%) followed by extensive adhesions (52.8%) were the leading causes for conversion to LSC. Aberrant biliary anatomy was the strongest predictor of conversion, and an emergency operation was more likely to require a LSC. The presence of a contracted gallbladder, severe inflammation, gallbladder empyema and extensive adhesions were all independently associated with LSC (all p < 0.05). Postoperative complications were recorded in 26.4% of patients. Fifteen percent of patients had postoperative bile leaks; five resolved spontaneously while three required intervention with ERCP. There were eight Clavien-Dindo Grade III complications, three (5.7%) required ERCPs and five (9.4%) required relook laparotomies. There was one mortality. Conclusions: LSC is a safe alternative that should be utilized in the management of complex gallbladder pathology. Post-operative bile leak was not a major clinical issue in our settingen_US
dc.identifier.apacitationBooyse, K. (2023). <i>Risk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centre</i>. (). ,Faculty of Health Sciences ,Division of General Surgery. Retrieved from http://hdl.handle.net/11427/37971en_ZA
dc.identifier.chicagocitationBooyse, Karien. <i>"Risk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centre."</i> ., ,Faculty of Health Sciences ,Division of General Surgery, 2023. http://hdl.handle.net/11427/37971en_ZA
dc.identifier.citationBooyse, K. 2023. Risk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centre. . ,Faculty of Health Sciences ,Division of General Surgery. http://hdl.handle.net/11427/37971en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Booyse, Karien AB - Background: Laparoscopic subtotal cholecystectomy (LSC) is utilized as a safe and feasible alternative for difficult cholecystectomies to avoid bile duct injury and can aid in avoiding conversion to open surgery. This study assesses the risk factors and outcomes of patients who underwent LSC. Methods: A retrospective analysis was conducted of patients undergoing LSC from September 2019 to August 2021. Relative clinical and operative factors as well as postoperative outcomes were analysed. Results: There were 631 consecutive cholecystectomies included, 53 of which required LSC. Nine (16.9%) used the reconstituting technique and 43 (81.8%) were fenestrating LSC, one procedure not specified. High BMI (26.4%) and previous endoscopic retrograde cholangiopancreatography (ERCP) (18.9%) were the most common indicators for expected difficulty. Severe inflammation (58.5%) followed by extensive adhesions (52.8%) were the leading causes for conversion to LSC. Aberrant biliary anatomy was the strongest predictor of conversion, and an emergency operation was more likely to require a LSC. The presence of a contracted gallbladder, severe inflammation, gallbladder empyema and extensive adhesions were all independently associated with LSC (all p < 0.05). Postoperative complications were recorded in 26.4% of patients. Fifteen percent of patients had postoperative bile leaks; five resolved spontaneously while three required intervention with ERCP. There were eight Clavien-Dindo Grade III complications, three (5.7%) required ERCPs and five (9.4%) required relook laparotomies. There was one mortality. Conclusions: LSC is a safe alternative that should be utilized in the management of complex gallbladder pathology. Post-operative bile leak was not a major clinical issue in our setting DA - 2023 DB - OpenUCT DP - University of Cape Town KW - Surgery LK - https://open.uct.ac.za PY - 2023 T1 - Risk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centre TI - Risk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centre UR - http://hdl.handle.net/11427/37971 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/37971
dc.identifier.vancouvercitationBooyse K. Risk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centre. []. ,Faculty of Health Sciences ,Division of General Surgery, 2023 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/37971en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDivision of General Surgeryen_US
dc.publisher.facultyFaculty of Health Sciencesen_US
dc.subjectSurgeryen_US
dc.titleRisk Factors Predicting Conversion to Laparoscopic Subtotal Cholecystectomy and Post-operative Outcomes from a High-Volume Centreen_US
dc.typeThesis / Dissertationen_US
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