Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review
| dc.contributor.advisor | Tinley, Christopher | |
| dc.contributor.author | Steyn, Anna | |
| dc.date.accessioned | 2020-04-22T22:34:33Z | |
| dc.date.available | 2020-04-22T22:34:33Z | |
| dc.date.issued | 2019 | |
| dc.date.updated | 2020-04-22T22:33:49Z | |
| dc.description.abstract | OBJECTIVES: To describe the clinical features of Duane’s retraction syndrome in a cohort of South African children and analyse subtypes for ethnic differences. METHODS: Retrospective case series of 120 patients seen in the period from 1997 to 2017 at the Red Cross War Memorial Children’s Hospital. RESULTS: Of the 120 patients, Type 1 was present in 76 (64%) of cases, with Type 2 in 27 (23%) and Type 3 in 16 (13%).Type 2 was most common in black children (54%), while Type 1 predominated in mixed race (68%) and white children (94%). A female predominance was seen in white children (69%) and mixed race children (59%), while there was a male predominance amongst black children (62.5%) Left involvement was the most common (44%), followed by right (41%) and bilateral involvement (14%).The average age of presentation was 2,85 years. A positive family history of squints or Duane’s was present in 6 (0,5%). Congenital systemic abnormalities were present in 12 (1%) and congenital ocular abnormalities in 2 (0.4%). Squint in primary position was present in 57 (46%), of which 39% had esotropia and 61% exotropia. Squint was more common in black children (71%) than in mixed race (39.4%) and white children (41%). An abnormal head position was present in 59 (50%) and was most common in Type 2 (67%). Up and downshoots were seen in 58 (48.3%). Ametropia was found in 94 (79%), and of these 88 (93,6%) were hyperopic and 6 (6.4%) myopic. Amblyopia was present in 15 (12.5%). Surgery was performed in 41(34%). CONCLUSION: This study is the first to provide robust data on the profile of paediatric DRS in the 3 main South African ethnic groups, and shows clear ethnic differences in DRS. In black patients, males are more often affected, the proportion with Type 2 DRS is more frequent, and surgery is required more often. Further population-based studies on the epidemiology of DRS in children are needed to clarify the role of race as a potential risk factor. | |
| dc.identifier.apacitation | Steyn, A. (2019). <i>Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review</i>. (). ,Faculty of Health Sciences ,Division of Ophthalmology. Retrieved from | en_ZA |
| dc.identifier.chicagocitation | Steyn, Anna. <i>"Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review."</i> ., ,Faculty of Health Sciences ,Division of Ophthalmology, 2019. | en_ZA |
| dc.identifier.citation | Steyn, A. 2019. Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review. . ,Faculty of Health Sciences ,Division of Ophthalmology. | en_ZA |
| dc.identifier.ris | TY - Thesis / Dissertation AU - Steyn, Anna AB - OBJECTIVES: To describe the clinical features of Duane’s retraction syndrome in a cohort of South African children and analyse subtypes for ethnic differences. METHODS: Retrospective case series of 120 patients seen in the period from 1997 to 2017 at the Red Cross War Memorial Children’s Hospital. RESULTS: Of the 120 patients, Type 1 was present in 76 (64%) of cases, with Type 2 in 27 (23%) and Type 3 in 16 (13%).Type 2 was most common in black children (54%), while Type 1 predominated in mixed race (68%) and white children (94%). A female predominance was seen in white children (69%) and mixed race children (59%), while there was a male predominance amongst black children (62.5%) Left involvement was the most common (44%), followed by right (41%) and bilateral involvement (14%).The average age of presentation was 2,85 years. A positive family history of squints or Duane’s was present in 6 (0,5%). Congenital systemic abnormalities were present in 12 (1%) and congenital ocular abnormalities in 2 (0.4%). Squint in primary position was present in 57 (46%), of which 39% had esotropia and 61% exotropia. Squint was more common in black children (71%) than in mixed race (39.4%) and white children (41%). An abnormal head position was present in 59 (50%) and was most common in Type 2 (67%). Up and downshoots were seen in 58 (48.3%). Ametropia was found in 94 (79%), and of these 88 (93,6%) were hyperopic and 6 (6.4%) myopic. Amblyopia was present in 15 (12.5%). Surgery was performed in 41(34%). CONCLUSION: This study is the first to provide robust data on the profile of paediatric DRS in the 3 main South African ethnic groups, and shows clear ethnic differences in DRS. In black patients, males are more often affected, the proportion with Type 2 DRS is more frequent, and surgery is required more often. Further population-based studies on the epidemiology of DRS in children are needed to clarify the role of race as a potential risk factor. DA - 2019 DB - OpenUCT DP - University of Cape Town KW - Ophthalmology LK - https://open.uct.ac.za PY - 2019 T1 - Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review TI - Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review UR - ER - | en_ZA |
| dc.identifier.uri | https://hdl.handle.net/11427/31661 | |
| dc.identifier.vancouvercitation | Steyn A. Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review. []. ,Faculty of Health Sciences ,Division of Ophthalmology, 2019 [cited yyyy month dd]. Available from: | en_ZA |
| dc.language.rfc3066 | eng | |
| dc.publisher.department | Division of Ophthalmology | |
| dc.publisher.faculty | Faculty of Health Sciences | |
| dc.subject | Ophthalmology | |
| dc.title | Duane's retraction syndrome in a cohort of South African children a 20 year clinic based review | |
| dc.type | Master Thesis | |
| dc.type.qualificationlevel | Masters | |
| dc.type.qualificationname | MMed |