Guideline for the management of acute asthma in adults: 2013 update

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dc.contributor.authorLalloo, U G
dc.contributor.authorAinslie, G M
dc.contributor.authorAbdool-Gaffar, M S
dc.contributor.authorAwotedu, A A
dc.contributor.authorFeldman, C
dc.contributor.authorGreenblatt, M
dc.contributor.authorIRUSEN, E M
dc.contributor.authorMash, R
dc.contributor.authorNaidoo, S S
dc.contributor.authorO\'Brien, J
dc.contributor.authorOtto, W
dc.contributor.authorRichards, G A
dc.contributor.authorWong,, M L
dc.date.accessioned2021-10-08T07:18:04Z
dc.date.available2021-10-08T07:18:04Z
dc.date.issued2013
dc.description.abstractAcute asthma attacks (asthma exacerbations) are increasing episodes of shortness of breath, cough, wheezing or chest tightness associated with a decrease in airflow that can be quantified and monitored by measurement of lung function (peak expiratory flow (PEF) or forced expiratory volume in the 1st second) and requiring emergency room treatment or admission to hospital for acute asthma and/or systemic glucocorticosteroids for management. The goals of treatment are to relieve hypoxaemia and airflow obstruction as quickly as possible, restore lung function, and provide a suitable plan to avoid relapse. Severe exacerbations are potentially life-threatening and their treatment requires baseline assessment of severity, close monitoring, and frequent reassessment using objective measures of lung function (PEF) and oxygen saturation. Patients at high risk of asthma-related death require particular attention. First-line therapy consists of oxygen supplementation, repeated administration of inhaled short-acting bronchodilators (beta-2-agonists and ipratropium bromide), and early systemic glucocorticosteroids. Intravenous magnesium sulphate and aminophylline are second- and third-line treatment strategies, respectively, for poorly responding patients. Intensive care is indicated for severe asthma that is not responsive to first-line treatment. Antibiotics are only indicated when there are definite features of bacterial infection. Factors that precipitated the acute asthma episode should be identified and preventive measures implemented. Acute asthma is preventable with optimal control of chronic asthma.
dc.identifier.apacitationLalloo, U. G., Ainslie, G. M., Abdool-Gaffar, M. S., Awotedu, A. A., Feldman, C., Greenblatt, M., ... (2013). Guideline for the management of acute asthma in adults: 2013 update. <i>South African Medical Journal</i>, 103(3), 189 - 177. http://hdl.handle.net/11427/34897en_ZA
dc.identifier.chicagocitationLalloo, U G, G M Ainslie, M S Abdool-Gaffar, A A Awotedu, C Feldman, M Greenblatt, E M IRUSEN, et al "Guideline for the management of acute asthma in adults: 2013 update." <i>South African Medical Journal</i> 103, 3. (2013): 189 - 177. http://hdl.handle.net/11427/34897en_ZA
dc.identifier.citationLalloo, U.G., Ainslie, G.M., Abdool-Gaffar, M.S., Awotedu, A.A., Feldman, C., Greenblatt, M., IRUSEN, E.M. & Mash, R. et al. 2013. Guideline for the management of acute asthma in adults: 2013 update. <i>South African Medical Journal.</i> 103(3):189 - 177. http://hdl.handle.net/11427/34897en_ZA
dc.identifier.issn0038-2469
dc.identifier.ris TY - Journal Article AU - Lalloo, U G AU - Ainslie, G M AU - Abdool-Gaffar, M S AU - Awotedu, A A AU - Feldman, C AU - Greenblatt, M AU - IRUSEN, E M AU - Mash, R AU - Naidoo, S S AU - O\'Brien, J AU - Otto, W AU - Richards, G A AU - Wong,, M L AB - Acute asthma attacks (asthma exacerbations) are increasing episodes of shortness of breath, cough, wheezing or chest tightness associated with a decrease in airflow that can be quantified and monitored by measurement of lung function (peak expiratory flow (PEF) or forced expiratory volume in the 1st second) and requiring emergency room treatment or admission to hospital for acute asthma and/or systemic glucocorticosteroids for management. The goals of treatment are to relieve hypoxaemia and airflow obstruction as quickly as possible, restore lung function, and provide a suitable plan to avoid relapse. Severe exacerbations are potentially life-threatening and their treatment requires baseline assessment of severity, close monitoring, and frequent reassessment using objective measures of lung function (PEF) and oxygen saturation. Patients at high risk of asthma-related death require particular attention. First-line therapy consists of oxygen supplementation, repeated administration of inhaled short-acting bronchodilators (beta-2-agonists and ipratropium bromide), and early systemic glucocorticosteroids. Intravenous magnesium sulphate and aminophylline are second- and third-line treatment strategies, respectively, for poorly responding patients. Intensive care is indicated for severe asthma that is not responsive to first-line treatment. Antibiotics are only indicated when there are definite features of bacterial infection. Factors that precipitated the acute asthma episode should be identified and preventive measures implemented. Acute asthma is preventable with optimal control of chronic asthma. DA - 2013 DB - OpenUCT DP - University of Cape Town IS - 3 J1 - South African Medical Journal LK - https://open.uct.ac.za PY - 2013 SM - 0038-2469 T1 - Guideline for the management of acute asthma in adults: 2013 update TI - Guideline for the management of acute asthma in adults: 2013 update UR - http://hdl.handle.net/11427/34897 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34897
dc.identifier.vancouvercitationLalloo UG, Ainslie GM, Abdool-Gaffar MS, Awotedu AA, Feldman C, Greenblatt M, et al. Guideline for the management of acute asthma in adults: 2013 update. South African Medical Journal. 2013;103(3):189 - 177. http://hdl.handle.net/11427/34897.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceSouth African Medical Journal
dc.source.journalissue3
dc.source.journalvolume103
dc.source.pagination189 - 177
dc.source.urihttps://dx.doi.org/10.7196/SAMJ.6526
dc.subject.otherCough
dc.subject.otherBacterial Infections
dc.subject.otherDeath
dc.subject.otherAsthma
dc.subject.otherRecurrence
dc.subject.otherRespiratory Sounds
dc.subject.otherDyspnea
dc.subject.otherThorax
dc.subject.otherLung
dc.subject.otherAminophylline
dc.subject.otherMagnesium
dc.subject.otherBronchodilator Agents
dc.subject.otherOxygen
dc.subject.otherIpratropium
dc.subject.otherEmergency Treatment
dc.subject.otherTherapeutics
dc.subject.otherForced Expiratory Volume
dc.subject.otherIntensive Care
dc.subject.otherRisk
dc.subject.otherAcute Asthma
dc.titleGuideline for the management of acute asthma in adults: 2013 update
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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