The compounding effects of obesity on the development of Intimal Hyperplasia following vascular intervention : a histopathological analysis
Master Thesis
2009
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University of Cape Town
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Abstract
This study examines the histopathological response to injury following both balloon angioplasty and endovascular stenting in the Zucker rat, a model that allows interpretation of the role of obesity as well as progressive glucose intolerance and hyperinsulimaemia. Lean and obese Zucker fatty rats and Zucker diabetic fatty rat (ZDF) were subjected to balloon injury with or without stenting. The development of IH, along with the histological response to injury was analyzed.
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Includes abstract.
Includes bibliographical references (leaves 100-111).
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Black, M. 2009. The compounding effects of obesity on the development of Intimal Hyperplasia following vascular intervention : a histopathological analysis. University of Cape Town.