Cardiovascular prevention: lifestyle and statins – competitors or companions?

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dc.contributor.authorOpie, Lionel Henry
dc.contributor.authorDalby, Anthony John
dc.date.accessioned2021-10-08T07:20:27Z
dc.date.available2021-10-08T07:20:27Z
dc.date.issued2014
dc.description.abstractFavourable lifestyles promote cardiovascular protection. Exercise can induce beneficial changes in the genome that decrease low-density lipoprotein cholesterol (LDL-C) and increase anti-inflammatory markers. The Mediterranean dietary pattern, fortified by nuts, while not reducing weight, reduces mortality. Lifestyle changes combined with statin therapy provide potent protection against coronary heart disease, especially when used for secondary prevention after cardiovascular events. Decisions regarding the initiation of statin therapy for primary prevention are more difficult, requiring consideration of both the LDL-C level and the degree of cardiovascular risk for dyslipidaemic patients. Combining intensive exercise and statin therapy substantially reduces the mortality risk, and thus is potentially the ideal risk-reducing combination.
dc.identifier.apacitationOpie, L. H., & Dalby, A. J. (2014). Cardiovascular prevention: lifestyle and statins – competitors or companions?. <i>South African Medical Journal</i>, 104(3), 168 - 177. http://hdl.handle.net/11427/34918en_ZA
dc.identifier.chicagocitationOpie, Lionel Henry, and Anthony John Dalby "Cardiovascular prevention: lifestyle and statins – competitors or companions?." <i>South African Medical Journal</i> 104, 3. (2014): 168 - 177. http://hdl.handle.net/11427/34918en_ZA
dc.identifier.citationOpie, L.H. & Dalby, A.J. 2014. Cardiovascular prevention: lifestyle and statins – competitors or companions?. <i>South African Medical Journal.</i> 104(3):168 - 177. http://hdl.handle.net/11427/34918en_ZA
dc.identifier.issn0038-2469
dc.identifier.ris TY - Journal Article AU - Opie, Lionel Henry AU - Dalby, Anthony John AB - Favourable lifestyles promote cardiovascular protection. Exercise can induce beneficial changes in the genome that decrease low-density lipoprotein cholesterol (LDL-C) and increase anti-inflammatory markers. The Mediterranean dietary pattern, fortified by nuts, while not reducing weight, reduces mortality. Lifestyle changes combined with statin therapy provide potent protection against coronary heart disease, especially when used for secondary prevention after cardiovascular events. Decisions regarding the initiation of statin therapy for primary prevention are more difficult, requiring consideration of both the LDL-C level and the degree of cardiovascular risk for dyslipidaemic patients. Combining intensive exercise and statin therapy substantially reduces the mortality risk, and thus is potentially the ideal risk-reducing combination. DA - 2014 DB - OpenUCT DP - University of Cape Town IS - 3 J1 - South African Medical Journal LK - https://open.uct.ac.za PY - 2014 SM - 0038-2469 T1 - Cardiovascular prevention: lifestyle and statins – competitors or companions? TI - Cardiovascular prevention: lifestyle and statins – competitors or companions? UR - http://hdl.handle.net/11427/34918 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34918
dc.identifier.vancouvercitationOpie LH, Dalby AJ. Cardiovascular prevention: lifestyle and statins – competitors or companions?. South African Medical Journal. 2014;104(3):168 - 177. http://hdl.handle.net/11427/34918.en_ZA
dc.language.isoeng
dc.publisher.departmentCardiovascular Research Unit
dc.publisher.facultyFaculty of Health Sciences
dc.sourceSouth African Medical Journal
dc.source.journalissue3
dc.source.journalvolume104
dc.source.pagination168 - 177
dc.source.urihttps://dx.doi.org/10.7196/SAMJ.7942
dc.subject.otherCardiovascular Diseases
dc.subject.otherDiet
dc.subject.otherExercise
dc.subject.otherHumans
dc.subject.otherHydroxymethylglutaryl-CoA Reductase Inhibitors
dc.subject.otherLife Style
dc.subject.otherHydroxymethylglutaryl-CoA Reductase Inhibitors
dc.titleCardiovascular prevention: lifestyle and statins – competitors or companions?
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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