A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids

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dc.contributor.advisorRobins, A Hen_ZA
dc.contributor.authorRottanburg, Dawnen_ZA
dc.date.accessioned2018-02-05T12:43:01Z
dc.date.available2018-02-05T12:43:01Z
dc.date.issued1982en_ZA
dc.description.abstractMany South African psychiatrists, and particularly those working in psychiatric hospitals with Black and Coloured patients, have the firm clinical impression that in many of these patients acute psychotic illness is associated with the abuse of cannabis. Most of the previous work in this field had been done by clinicians of Eastern countries where the use of cannabis has been endemic for thousands of years. However, those workers were handicapped because they lacked both the sophisticated techniques for standardized psychiatric evaluation and the availability of an assay to confirm cannabis use. It was decided to investigate acute psychoses in Cape Coloured males admitted to Valkenberg Hospital with the following aims: i. To identify a cohort of acutely psychotic patients who had recently been using cannabis and to compare them with a matched control group who were free of any drugs. The recently available EMITR immunochemical analytical technique was used for the detection of urinary cannabinoids. To exclude the contribution of other psychotropic agents to the aetiology of the psychoses, gas chromatography was performed to detect ethanol and thin-layer chromatography to screen for other psychotropic agents. ii. To assess the comprehensive mental state of patients on admission and then again after a 7-10 day period the Present State Examination (PSE), a well validated and standardized diagnostic instrument, was used. iii. To determine serum creatinine phosphokinase (CPK) and serum lactate dehydrogenase (LDH) levels (indicators of muscle damage) in view of the published reports of elevated levels in psychotic patients.en_ZA
dc.identifier.apacitationRottanburg, D. (1982). <i>A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health. Retrieved from http://hdl.handle.net/11427/27272en_ZA
dc.identifier.chicagocitationRottanburg, Dawn. <i>"A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health, 1982. http://hdl.handle.net/11427/27272en_ZA
dc.identifier.citationRottanburg, D. 1982. A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Rottanburg, Dawn AB - Many South African psychiatrists, and particularly those working in psychiatric hospitals with Black and Coloured patients, have the firm clinical impression that in many of these patients acute psychotic illness is associated with the abuse of cannabis. Most of the previous work in this field had been done by clinicians of Eastern countries where the use of cannabis has been endemic for thousands of years. However, those workers were handicapped because they lacked both the sophisticated techniques for standardized psychiatric evaluation and the availability of an assay to confirm cannabis use. It was decided to investigate acute psychoses in Cape Coloured males admitted to Valkenberg Hospital with the following aims: i. To identify a cohort of acutely psychotic patients who had recently been using cannabis and to compare them with a matched control group who were free of any drugs. The recently available EMITR immunochemical analytical technique was used for the detection of urinary cannabinoids. To exclude the contribution of other psychotropic agents to the aetiology of the psychoses, gas chromatography was performed to detect ethanol and thin-layer chromatography to screen for other psychotropic agents. ii. To assess the comprehensive mental state of patients on admission and then again after a 7-10 day period the Present State Examination (PSE), a well validated and standardized diagnostic instrument, was used. iii. To determine serum creatinine phosphokinase (CPK) and serum lactate dehydrogenase (LDH) levels (indicators of muscle damage) in view of the published reports of elevated levels in psychotic patients. DA - 1982 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 1982 T1 - A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids TI - A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids UR - http://hdl.handle.net/11427/27272 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/27272
dc.identifier.vancouvercitationRottanburg D. A toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoids. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health, 1982 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/27272en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Psychiatry and Mental Healthen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherClinical Psychiatryen_ZA
dc.subject.otherCannabinoids - Adverse effectsen_ZA
dc.subject.otherCannabis Abuse - psychologyen_ZA
dc.subject.otherPsychoses, Substance-induced - South Africa - Cape Colouredsen_ZA
dc.titleA toxicological survey of acute psychoses in Cape Coloured males with special reference to the cannabinoidsen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMSc (Med)en_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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