Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat

Simple item page
dc.contributor.authorAkilimali, Aymar
dc.contributor.authorBisimwa, Charles
dc.contributor.authorAborode, Abdullahi T.
dc.contributor.authorBiamba, Chrispin
dc.contributor.authorSironge, Leonard
dc.contributor.authorBalume, Alain
dc.contributor.authorSayadi, Rahma
dc.contributor.authorAjibade, Samuel B.
dc.contributor.authorAkintayo, Akintola A.
dc.contributor.authorOluwadairo, Tolulope O.
dc.contributor.authorFajemisin, Emmanuel A.
dc.date.accessioned2023-09-18T10:36:43Z
dc.date.available2023-09-18T10:36:43Z
dc.date.issued2022-10-04
dc.date.updated2022-10-09T03:10:16Z
dc.description.abstractBackground Malaria is a global infectious (vector-borne: Anopheles mosquitoes) disease which is a leading cause of morbidity and mortality in Sub-Saharan Africa (SSA). Among all its parasitic (protozoan: Plasmodium sp.) variants, Plasmodium falciparum (PF) is the most virulent and responsible for above 90% of global malaria deaths hence making it a global public health threat. Main context Despite current front-line antimalarial treatments options especially allopathic medications and malaria prevention (and control) strategies especially governmental policies and community malaria intervention programs in SSA, PF infections remains prevalent due to increased antimicrobial/antimalarial drug resistance caused by several factors especially genetic mutations and auto(self)-medication practices in SSA. In this article, we focused on the Democratic Republic of Congo (DRC) as the largest SSA country by bringing perspective into the impact of self-medication and antimalarial drug resistance, and provided recommendation for long-term improvement and future analysis in malaria prevention and control in SSA. Conclusions Self-medication and anti-malarial drug resistance is a major challenge to malaria control in DRC and sub-Saharan Africa, and to achieve sustainable control, individual, community and governmental efforts must be aligned to stop self-medication, and strengthen the health systems against malaria.
dc.identifier.apacitationAkilimali, A., Bisimwa, C., Aborode, Abdullahi T., Biamba, C., Sironge, L., Balume, A., ... Fajemisin, Emmanuel A. (2022). Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat. <i>Tropical Medicine and Health</i>, 50(1), 73. http://hdl.handle.net/11427/38724en_ZA
dc.identifier.chicagocitationAkilimali, Aymar, Charles Bisimwa, Abdullahi T. Aborode, Chrispin Biamba, Leonard Sironge, Alain Balume, Rahma Sayadi, et al "Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat." <i>Tropical Medicine and Health</i> 50, 1. (2022): 73. http://hdl.handle.net/11427/38724en_ZA
dc.identifier.citationAkilimali, A., Bisimwa, C., Aborode, Abdullahi T., Biamba, C., Sironge, L., Balume, A., Sayadi, R. & Ajibade, Samuel B. et al. 2022. Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat. <i>Tropical Medicine and Health.</i> 50(1):73. http://hdl.handle.net/11427/38724en_ZA
dc.identifier.ris TY - Journal Article AU - Akilimali, Aymar AU - Bisimwa, Charles AU - Aborode, Abdullahi T. AU - Biamba, Chrispin AU - Sironge, Leonard AU - Balume, Alain AU - Sayadi, Rahma AU - Ajibade, Samuel B. AU - Akintayo, Akintola A. AU - Oluwadairo, Tolulope O. AU - Fajemisin, Emmanuel A. AB - Background Malaria is a global infectious (vector-borne: Anopheles mosquitoes) disease which is a leading cause of morbidity and mortality in Sub-Saharan Africa (SSA). Among all its parasitic (protozoan: Plasmodium sp.) variants, Plasmodium falciparum (PF) is the most virulent and responsible for above 90% of global malaria deaths hence making it a global public health threat. Main context Despite current front-line antimalarial treatments options especially allopathic medications and malaria prevention (and control) strategies especially governmental policies and community malaria intervention programs in SSA, PF infections remains prevalent due to increased antimicrobial/antimalarial drug resistance caused by several factors especially genetic mutations and auto(self)-medication practices in SSA. In this article, we focused on the Democratic Republic of Congo (DRC) as the largest SSA country by bringing perspective into the impact of self-medication and antimalarial drug resistance, and provided recommendation for long-term improvement and future analysis in malaria prevention and control in SSA. Conclusions Self-medication and anti-malarial drug resistance is a major challenge to malaria control in DRC and sub-Saharan Africa, and to achieve sustainable control, individual, community and governmental efforts must be aligned to stop self-medication, and strengthen the health systems against malaria. DA - 2022-10-04 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - Tropical Medicine and Health KW - Antimalarials KW - Drug resistance KW - Malaria KW - Self-medication KW - Democratic Republic of Congo LK - https://open.uct.ac.za PY - 2022 T1 - Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat TI - Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat UR - http://hdl.handle.net/11427/38724 ER - en_ZA
dc.identifier.urihttps://doi.org/10.1186/s41182-022-00466-9
dc.identifier.urihttp://hdl.handle.net/11427/38724
dc.identifier.vancouvercitationAkilimali A, Bisimwa C, Aborode Abdullahi T, Biamba C, Sironge L, Balume A, et al. Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat. Tropical Medicine and Health. 2022;50(1):73. http://hdl.handle.net/11427/38724.en_ZA
dc.language.rfc3066en
dc.publisherBioMed Central
dc.publisher.departmentIntegrative Biomedical Sciences
dc.publisher.facultyHealth Sciences
dc.rights.holderThe Author(s)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceTropical Medicine and Health
dc.source.journalissue1
dc.source.journalvolume50
dc.source.pagination73
dc.source.urihttps://tropmedhealth.biomedcentral.com/
dc.subjectAntimalarials
dc.subjectDrug resistance
dc.subjectMalaria
dc.subjectSelf-medication
dc.subjectDemocratic Republic of Congo
dc.titleSelf-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat
dc.typeJournal Article
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
41182_2022_Article_466.pdf
Size:
914.84 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
0 B
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal Articles