Cost-effectiveness analysis of introducing HTLV-1 testing in South Africa
Journal Article
2015
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Retrovirology
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BioMed Central Ltd
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University of Cape Town
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Abstract
We have previously reported a 2013 cross-sectional study of HTLV prevalence among 46,765 South African blood donors. Confirmed HTLV-1 prevalence was 0.16% in Black donors, 0.02% in both White and Coloured donors and 0% in south Asian donors, for an overall prevalence of 0.062% extrapolated to the current blood donor population. Using these data we estimated the cost effectiveness of potential HTLV screening strategies in preventing transfusion transmitted HTLV-1 infection (TTI). Five blood donor screening strategies were considered: no screening; HTLV testing of every donation; HTLV testing each donor one time only; HTLV testing of new donors only; and universal filter leukodepletion without HTLV testing.
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Reference:
Sykes, W., Coleman, C., Beck, G., Mhlanga, J., Hlela, C., Custer, B., ... & Vermeulen, M. (2015). Cost-effectiveness analysis of introducing HTLV-1 testing in South Africa. Retrovirology, 12(Suppl 1), P81.