Synthesis of naphtho{2,3-c}pyrans including the aphin-derived quinone A'
Master Thesis
1987
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University of Cape Town
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Abstract
Chapter One describes the synthesis of a trifluoroethylnaphtho-1, 4-quinone via a regiospecific trifluoroacetylation of an appropriately substituted naphthalene. Chapter Two describes the synthesis of the methyl ethers of the naturally occurring quinones A and deoxyquinone A for evaluation of their "anti-cancer" activity by the National Institutes of Health. In Chapter Three the final few steps of the synthesis of the aphid-derived quinone A' are described. This was made possible by the development of an efficient route for the conversion of a precursor to quinone A' via the corresponding chloro-derivative.
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Bibliography: pages 76-78.
Reference:
Ramdohr, J. 1987. Synthesis of naphtho{2,3-c}pyrans including the aphin-derived quinone A'. University of Cape Town.