Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population

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dc.contributor.advisorLubbe, Darleneen_ZA
dc.contributor.authorMonteiro, Pedro Vilas Boasen_ZA
dc.date.accessioned2015-12-10T09:30:15Z
dc.date.available2015-12-10T09:30:15Z
dc.date.issued2015en_ZA
dc.description.abstractStatement of problem: Topical corticosteroids nasal sprays remain first line of treatment for patients with chronic rhinosinusitis (with or without nasal polyps). The main aim of treatment is to improve nasal symptoms by reducing or eliminating the nasal polyps and preventing polyp recurrence post-operatively. Our aims were to determine if the type of corticosteroid nasal spray used post operatively influences polyp recurrence rate and if there were any subsequent economic implications as we only have beclomethasone available for prescription in our state hospital. Methods: Retrospective case note review of all Samter's patients who underwent fronto-spheno-ethmoidectomy by a single surgeon (2000 – 2014). Results: 58 patients were included in our study, divided into 3 study groups. When compared to patients using beclomethasone; patients using fluticasone had an 80% reduced risk of polyp recurrence and patients using mometasone a 90% reduced risk. This rose to 88% and 96% respectively when adjusted for age. Conclusion: Fluticasone and mometasone are both statistically significantly more effective at reducing polyp recurrence than beclomethasone in our population group. Mometasone appeared more effective than fluticasone, but this difference was not statistically significant.en_ZA
dc.identifier.apacitationMonteiro, P. V. B. (2015). <i>Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Otorhinolaryngology. Retrieved from http://hdl.handle.net/11427/15753en_ZA
dc.identifier.chicagocitationMonteiro, Pedro Vilas Boas. <i>"Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Otorhinolaryngology, 2015. http://hdl.handle.net/11427/15753en_ZA
dc.identifier.citationMonteiro, P. 2015. Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Monteiro, Pedro Vilas Boas AB - Statement of problem: Topical corticosteroids nasal sprays remain first line of treatment for patients with chronic rhinosinusitis (with or without nasal polyps). The main aim of treatment is to improve nasal symptoms by reducing or eliminating the nasal polyps and preventing polyp recurrence post-operatively. Our aims were to determine if the type of corticosteroid nasal spray used post operatively influences polyp recurrence rate and if there were any subsequent economic implications as we only have beclomethasone available for prescription in our state hospital. Methods: Retrospective case note review of all Samter's patients who underwent fronto-spheno-ethmoidectomy by a single surgeon (2000 – 2014). Results: 58 patients were included in our study, divided into 3 study groups. When compared to patients using beclomethasone; patients using fluticasone had an 80% reduced risk of polyp recurrence and patients using mometasone a 90% reduced risk. This rose to 88% and 96% respectively when adjusted for age. Conclusion: Fluticasone and mometasone are both statistically significantly more effective at reducing polyp recurrence than beclomethasone in our population group. Mometasone appeared more effective than fluticasone, but this difference was not statistically significant. DA - 2015 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2015 T1 - Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population TI - Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population UR - http://hdl.handle.net/11427/15753 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15753
dc.identifier.vancouvercitationMonteiro PVB. Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Otorhinolaryngology, 2015 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/15753en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Otorhinolaryngologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherOtorhinolaryngologyen_ZA
dc.titleComparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's populationen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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