Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.

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dc.contributor.advisorKellaway, Laurie Aen_ZA
dc.contributor.advisorSachs, NAen_ZA
dc.contributor.authorModak, Ghabibaen_ZA
dc.date.accessioned2015-01-10T13:35:20Z
dc.date.available2015-01-10T13:35:20Z
dc.date.issued2011en_ZA
dc.descriptionIncludes abstract.en_ZA
dc.descriptionIncludes bibliographical references.en_ZA
dc.description.abstractLower motor neuron damage often results in flaccid paralysis in which the affected muscles are unable to be stimulated artificially via the supplying nerve. Such damage is common in patients who suffer from spinal cord injury and Multiple Sclerosis. Current practice for artificial recovery of muscle function involves stimulating the muscles directly by means of Functional Electrical Stimulation (FES), which requires 100-1000 times more current than that required for nerve stimulation, thus presenting the risk of pain receptor activation. A potential alternative exists in chemical stimulation by means of administration of the neurotransmitter, Acetylcholine (ACh). This study investigates the potential of this possibility by examining the response of two muscle types to extracellular administration of ACh.en_ZA
dc.identifier.apacitationModak, G. (2011). <i>Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Biomedical Engineering. Retrieved from http://hdl.handle.net/11427/11994en_ZA
dc.identifier.chicagocitationModak, Ghabiba. <i>"Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Biomedical Engineering, 2011. http://hdl.handle.net/11427/11994en_ZA
dc.identifier.citationModak, G. 2011. Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Modak, Ghabiba AB - Lower motor neuron damage often results in flaccid paralysis in which the affected muscles are unable to be stimulated artificially via the supplying nerve. Such damage is common in patients who suffer from spinal cord injury and Multiple Sclerosis. Current practice for artificial recovery of muscle function involves stimulating the muscles directly by means of Functional Electrical Stimulation (FES), which requires 100-1000 times more current than that required for nerve stimulation, thus presenting the risk of pain receptor activation. A potential alternative exists in chemical stimulation by means of administration of the neurotransmitter, Acetylcholine (ACh). This study investigates the potential of this possibility by examining the response of two muscle types to extracellular administration of ACh. DA - 2011 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak TI - Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak UR - http://hdl.handle.net/11427/11994 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/11994
dc.identifier.vancouvercitationModak G. Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Biomedical Engineering, 2011 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/11994en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Biomedical Engineeringen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherBiomedical Engineeringen_ZA
dc.titleCharacterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.en_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMScen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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