The neural correlates of intimate partner violence in women

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dc.contributor.authorFlegar, S
dc.contributor.authorFouche, J P
dc.contributor.authorJordaan, E
dc.contributor.authorMarais, S
dc.contributor.authorSpottiswoode, B
dc.contributor.authorStein, Dan J
dc.contributor.authorVythilingum, B
dc.date.accessioned2017-04-26T09:19:48Z
dc.date.available2017-04-26T09:19:48Z
dc.date.issued2011
dc.date.updated2016-01-07T08:46:24Z
dc.description.abstractObjective: To examine hippocampal volume and white matter tracts in women with and without intimate partner violence (IPV). Method: Nineteen women with IPV exposure in the last year, and 21 women without IPV exposure in the last year underwent structural magnetic resonance imaging (MRI) including diffusion tensor imaging (DTI) sequences. Additional data on alcohol use and presence of psychiatric disorder was collected. Differences in fractional anisotropy (FA) between the two groups were examined, using a statistical model that included demographic measures, alcohol use and psychiatric disorder. Results: IPV subjects did not demonstrate significantly different hippocampal volumes compared to subjects without recent IPV. FA was, however, significantly reduced in the body of the corpus callosum of IPV subjects. Adjusting for age, alcohol use, smoking and psychiatric diagnosis did not change the significance of the result. Conclusion: Data on hippocampal volume in IPV are inconsistent, perhaps reflecting the fact that multiple factors influence this measure. Reduced FA in the body of the corpus callosum in IPV suggests altered integrity of this white matter tract; additional work is needed to address the underlying mechanisms and clinical correlates of this finding.
dc.identifier.apacitationFlegar, S., Fouche, J. P., Jordaan, E., Marais, S., Spottiswoode, B., Stein, D. J., & Vythilingum, B. (2011). The neural correlates of intimate partner violence in women. <i>African Journal of Psychiatry</i>, http://hdl.handle.net/11427/24223en_ZA
dc.identifier.chicagocitationFlegar, S, J P Fouche, E Jordaan, S Marais, B Spottiswoode, Dan J Stein, and B Vythilingum "The neural correlates of intimate partner violence in women." <i>African Journal of Psychiatry</i> (2011) http://hdl.handle.net/11427/24223en_ZA
dc.identifier.citationFlegar, S. J., Fouche, J. P., Jordaan, E., Marais, S., Spottiswoode, B., Stein, D. J., & Vythilingum, B. (2011). The neural correlates of intimate partner violence in women. African journal of psychiatry, 14(4), 310-314.
dc.identifier.ris TY - Journal Article AU - Flegar, S AU - Fouche, J P AU - Jordaan, E AU - Marais, S AU - Spottiswoode, B AU - Stein, Dan J AU - Vythilingum, B AB - Objective: To examine hippocampal volume and white matter tracts in women with and without intimate partner violence (IPV). Method: Nineteen women with IPV exposure in the last year, and 21 women without IPV exposure in the last year underwent structural magnetic resonance imaging (MRI) including diffusion tensor imaging (DTI) sequences. Additional data on alcohol use and presence of psychiatric disorder was collected. Differences in fractional anisotropy (FA) between the two groups were examined, using a statistical model that included demographic measures, alcohol use and psychiatric disorder. Results: IPV subjects did not demonstrate significantly different hippocampal volumes compared to subjects without recent IPV. FA was, however, significantly reduced in the body of the corpus callosum of IPV subjects. Adjusting for age, alcohol use, smoking and psychiatric diagnosis did not change the significance of the result. Conclusion: Data on hippocampal volume in IPV are inconsistent, perhaps reflecting the fact that multiple factors influence this measure. Reduced FA in the body of the corpus callosum in IPV suggests altered integrity of this white matter tract; additional work is needed to address the underlying mechanisms and clinical correlates of this finding. DA - 2011 DB - OpenUCT DP - University of Cape Town J1 - African Journal of Psychiatry LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - The neural correlates of intimate partner violence in women TI - The neural correlates of intimate partner violence in women UR - http://hdl.handle.net/11427/24223 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/24223
dc.identifier.vancouvercitationFlegar S, Fouche JP, Jordaan E, Marais S, Spottiswoode B, Stein DJ, et al. The neural correlates of intimate partner violence in women. African Journal of Psychiatry. 2011; http://hdl.handle.net/11427/24223.en_ZA
dc.language.isoeng
dc.publisher.departmentDepartment of Public Health and Family Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceAfrican Journal of Psychiatry
dc.source.urihttps://www.omicsonline.com/open-access/african-journal-of-psychiatry.php
dc.subject.otherCorpus callosum
dc.subject.otherHippocampal volume
dc.subject.otherIntimate partner violence
dc.subject.otherNeuroimaging
dc.titleThe neural correlates of intimate partner violence in women
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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