Estimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000

dc.contributor.authorNannan, Nadine
dc.contributor.authorNorman, Rosana
dc.contributor.authorHendricks, Michael
dc.contributor.authorDhansay, Muhammad A
dc.contributor.authorBradshaw, Debbie
dc.contributor.authorSouth African Comparative Risk Assessment Collaborating Group
dc.date.accessioned2017-05-12T13:29:45Z
dc.date.available2017-05-12T13:29:45Z
dc.date.issued2007
dc.date.updated2016-01-08T09:40:24Z
dc.description.abstractObjectives. To estimate the disease burden attributable to being underweight as an indicator of undernutrition in children under 5 years of age and in pregnant women for the year 2000. Design. World Health Organization comparative risk assessment (CRA) methodology was followed. The 1999 National Food Consumption Survey prevalence of underweight classified in three low weight-for-age categories was compared with standard growth charts to estimate population-attributable fractions for mortality and morbidity outcomes, based on increased risk for each category and applied to revised burden of disease estimates for South Africa in 2000. Maternal underweight, leading to an increased risk of intra-uterine growth retardation and further risk of low birth weight (LBW), was also assessed using the approach adopted by the global assessment. Monte Carlo simulation-modelling techniques were used for the uncertainty analysis. Setting. South Africa. Subjects. Children under 5 years of age and pregnant women. Outcome measures. Mortality and disability-adjusted life years (DALYs) from protein- energy malnutrition and a fraction of those from diarrhoeal disease, pneumonia, malaria, other nonHIV/AIDS infectious and parasitic conditions in children aged 0 - 4 years, and LBW. Results. Among children under 5 years, 11.8% were underweight. In the same age group, 11 808 deaths (95% uncertainty interval 11 100 - 12 642) or 12.3% (95% uncertainty interval 11.5 - 13.1%) were attributable to being underweight. Protein-energy malnutrition contributed 44.7% and diarrhoeal disease 29.6% of the total attributable burden. Childhood and maternal underweight accounted for 2.7% (95% uncertainty interval 2.6 - 2.9%) of all DALYs in South Africa in 2000 and 10.8% (95% uncertainty interval 10.2 - 11.5%) of DALYs in children under 5. Conclusions. The study shows that reduction of the occurrence of underweight would have a substantial impact on child mortality, and also highlights the need to monitor this important indicator of child health.
dc.identifier.apacitationNannan, N., Norman, R., Hendricks, M., Dhansay, M. A., Bradshaw, D., & (2007). Estimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000. <i>South African Medical Journal</i>, http://hdl.handle.net/11427/24281en_ZA
dc.identifier.chicagocitationNannan, Nadine, Rosana Norman, Michael Hendricks, Muhammad A Dhansay, Debbie Bradshaw, and "Estimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000." <i>South African Medical Journal</i> (2007) http://hdl.handle.net/11427/24281en_ZA
dc.identifier.citationNannan, N., Norman, R., Hendricks, M., Dhansay, M. A., Bradshaw, D., & Collaboration, S. A. C. R. A. (2007). Estimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000. South African Medical Journal, 97(8), 733-739.
dc.identifier.ris TY - Journal Article AU - Nannan, Nadine AU - Norman, Rosana AU - Hendricks, Michael AU - Dhansay, Muhammad A AU - Bradshaw, Debbie AU - South African Comparative Risk Assessment Collaborating Group AB - Objectives. To estimate the disease burden attributable to being underweight as an indicator of undernutrition in children under 5 years of age and in pregnant women for the year 2000. Design. World Health Organization comparative risk assessment (CRA) methodology was followed. The 1999 National Food Consumption Survey prevalence of underweight classified in three low weight-for-age categories was compared with standard growth charts to estimate population-attributable fractions for mortality and morbidity outcomes, based on increased risk for each category and applied to revised burden of disease estimates for South Africa in 2000. Maternal underweight, leading to an increased risk of intra-uterine growth retardation and further risk of low birth weight (LBW), was also assessed using the approach adopted by the global assessment. Monte Carlo simulation-modelling techniques were used for the uncertainty analysis. Setting. South Africa. Subjects. Children under 5 years of age and pregnant women. Outcome measures. Mortality and disability-adjusted life years (DALYs) from protein- energy malnutrition and a fraction of those from diarrhoeal disease, pneumonia, malaria, other nonHIV/AIDS infectious and parasitic conditions in children aged 0 - 4 years, and LBW. Results. Among children under 5 years, 11.8% were underweight. In the same age group, 11 808 deaths (95% uncertainty interval 11 100 - 12 642) or 12.3% (95% uncertainty interval 11.5 - 13.1%) were attributable to being underweight. Protein-energy malnutrition contributed 44.7% and diarrhoeal disease 29.6% of the total attributable burden. Childhood and maternal underweight accounted for 2.7% (95% uncertainty interval 2.6 - 2.9%) of all DALYs in South Africa in 2000 and 10.8% (95% uncertainty interval 10.2 - 11.5%) of DALYs in children under 5. Conclusions. The study shows that reduction of the occurrence of underweight would have a substantial impact on child mortality, and also highlights the need to monitor this important indicator of child health. DA - 2007 DB - OpenUCT DP - University of Cape Town J1 - South African Medical Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2007 T1 - Estimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000 TI - Estimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000 UR - http://hdl.handle.net/11427/24281 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/24281
dc.identifier.vancouvercitationNannan N, Norman R, Hendricks M, Dhansay MA, Bradshaw D, . Estimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000. South African Medical Journal. 2007; http://hdl.handle.net/11427/24281.en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Child and Adolescent Psychiatryen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.sourceSouth African Medical Journal
dc.source.urihttp://www.ajol.info/index.php/samj/article/view/13904/59683
dc.titleEstimating the burden of disease attributable to childhood and maternal undernutrition in South Africa in 2000
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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