Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa

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dc.contributor.authorAdeola, Henry A
dc.contributor.authorSoyele, Olujide O
dc.contributor.authorAdefuye, Anthonio O
dc.contributor.authorJimoh, Sikiru A
dc.contributor.authorButali, Azeez
dc.date.accessioned2021-10-08T06:54:59Z
dc.date.available2021-10-08T06:54:59Z
dc.date.issued2017
dc.description.abstractBACKGROUND: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and "big data" processing have contributed immensely to individualized/personalized medicine in the developed world. MAIN BODY: At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratification of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the proficiency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among different human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences. CONCLUSION: In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting.
dc.identifier.apacitationAdeola, H. A., Soyele, O. O., Adefuye, A. O., Jimoh, S. A., & Butali, A. (2017). Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. <i>Cancer Cell International</i>, 17(1), 174 - 177. http://hdl.handle.net/11427/34390en_ZA
dc.identifier.chicagocitationAdeola, Henry A, Olujide O Soyele, Anthonio O Adefuye, Sikiru A Jimoh, and Azeez Butali "Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa." <i>Cancer Cell International</i> 17, 1. (2017): 174 - 177. http://hdl.handle.net/11427/34390en_ZA
dc.identifier.citationAdeola, H.A., Soyele, O.O., Adefuye, A.O., Jimoh, S.A. & Butali, A. 2017. Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. <i>Cancer Cell International.</i> 17(1):174 - 177. http://hdl.handle.net/11427/34390en_ZA
dc.identifier.issn1475-2867
dc.identifier.ris TY - Journal Article AU - Adeola, Henry A AU - Soyele, Olujide O AU - Adefuye, Anthonio O AU - Jimoh, Sikiru A AU - Butali, Azeez AB - BACKGROUND: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and "big data" processing have contributed immensely to individualized/personalized medicine in the developed world. MAIN BODY: At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratification of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the proficiency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among different human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences. CONCLUSION: In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting. DA - 2017 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - Cancer Cell International LK - https://open.uct.ac.za PY - 2017 SM - 1475-2867 T1 - Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa TI - Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa UR - http://hdl.handle.net/11427/34390 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/34390
dc.identifier.vancouvercitationAdeola HA, Soyele OO, Adefuye AO, Jimoh SA, Butali A. Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa. Cancer Cell International. 2017;17(1):174 - 177. http://hdl.handle.net/11427/34390.en_ZA
dc.publisher.departmentDepartment of Medicine
dc.publisher.facultyFaculty of Health Sciences
dc.sourceCancer Cell International
dc.source.journalissue1
dc.source.journalvolume17
dc.source.pagination174 - 177
dc.source.urihttps://dx.doi.org/10.1186/s12935-017-0432-8
dc.subject.otherChallenges
dc.subject.otherDeveloping world
dc.subject.otherMolecular
dc.subject.otherOmics-based
dc.subject.otherOral pathology
dc.titleOmics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa
dc.typeJournal Article
uct.type.publicationResearch
uct.type.resourceJournal Article
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