Identification of the virulence gene of Mycobacterium tuberculosis

Master Thesis

2007

Permanent link to this Item
http://hdl.handle.net/11427/4325
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thesis_sci_2007_rabiu_ha.pdf (7.09 MB)
Authors
Rabiu, Halimah Adenike
Supervisors
Mulder, Nicola
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University of Cape Town

Department
Department of Molecular and Cell Biology
Faculty
Faculty of Science
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Abstract
The major thrust of this project is to identify and characterize potential virulence genes from M. tuberculosis. To this end, we have compiled and integrated information from various public databases to catalogue 246573 microbial genes from 84 organisms, including pathogens and non pathogenic microbes. We determined the phylogenetic distributions by grouping the proteins into families based on sequence similarity with the aid of BLASTP and the NCBI BLASTClust program.
Description

Includes bibliographical references (leaves [103]-119).

Keywords
Bioinformatics

Reference:

Rabiu, H. 2007. Identification of the virulence gene of Mycobacterium tuberculosis. University of Cape Town.

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Masters