Cognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital population

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dc.contributor.advisorSolms, Marken_ZA
dc.contributor.authorPantelis, Elenien_ZA
dc.date.accessioned2014-10-03T12:50:41Z
dc.date.available2014-10-03T12:50:41Z
dc.date.issued2005en_ZA
dc.description.abstractSubarachnoid haemorrhage secondary to ruptured cerebral aneurysm and clipping are associated with substantial morbidity and mortality. Despite favourable neurological outcomes, many patients report persistent cognitive and emotional deficits post intervention. To compare cognitive and quality of life outcomes in patients with ruptured aneurysmal subarachnoid haemorrhage treated with surgical clipping or endovascular coiling. Twenty-four patients with aneurysmal subarachnoid haemorrhage treated by clipping or coiling were retrospectively assessed by use of a battery of cognitive tests and a quality of life questionnaire. All patients had favourable grades on admission, that is, WFNS <= 2 and favourable neurological grades on discharge, that is, GOS <=2. treated with surgical clipping or endovascular coiling. Patients in the two treatment groups were matched on age, years of education and on premorbid IQ. The two groups were further matched on time from intervention to assessment and number of treatments. The cognitive performance of the treatment groups was compared to hospitalised controls, matched for age, years of education and premorbid IQ. Comparison of cognitive outcome between the two groups indicated a trend towards poorer outcome in the surgical group which achieved significance on six test measures. There were no significant differences with respect to the quality of life measure. Patients surviving aneurysmal subarachnoid haemorrhage are likely to suffer from a 'subarachnoid-induced encephalopathy' which appears to be more aggravated by the invasive nature of surgery, compared to endovascular coiling, as demonstrated by the poorer cognitive performance ofthe clipping patients.en_ZA
dc.identifier.apacitationPantelis, E. (2005). <i>Cognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital population</i>. (Thesis). University of Cape Town ,Faculty of Humanities ,Department of Psychology. Retrieved from http://hdl.handle.net/11427/8041en_ZA
dc.identifier.chicagocitationPantelis, Eleni. <i>"Cognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital population."</i> Thesis., University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2005. http://hdl.handle.net/11427/8041en_ZA
dc.identifier.citationPantelis, E. 2005. Cognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital population. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Pantelis, Eleni AB - Subarachnoid haemorrhage secondary to ruptured cerebral aneurysm and clipping are associated with substantial morbidity and mortality. Despite favourable neurological outcomes, many patients report persistent cognitive and emotional deficits post intervention. To compare cognitive and quality of life outcomes in patients with ruptured aneurysmal subarachnoid haemorrhage treated with surgical clipping or endovascular coiling. Twenty-four patients with aneurysmal subarachnoid haemorrhage treated by clipping or coiling were retrospectively assessed by use of a battery of cognitive tests and a quality of life questionnaire. All patients had favourable grades on admission, that is, WFNS &amp;amp;lt;= 2 and favourable neurological grades on discharge, that is, GOS &amp;amp;lt;=2. treated with surgical clipping or endovascular coiling. Patients in the two treatment groups were matched on age, years of education and on premorbid IQ. The two groups were further matched on time from intervention to assessment and number of treatments. The cognitive performance of the treatment groups was compared to hospitalised controls, matched for age, years of education and premorbid IQ. Comparison of cognitive outcome between the two groups indicated a trend towards poorer outcome in the surgical group which achieved significance on six test measures. There were no significant differences with respect to the quality of life measure. Patients surviving aneurysmal subarachnoid haemorrhage are likely to suffer from a 'subarachnoid-induced encephalopathy' which appears to be more aggravated by the invasive nature of surgery, compared to endovascular coiling, as demonstrated by the poorer cognitive performance ofthe clipping patients. DA - 2005 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2005 T1 - Cognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital population TI - Cognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital population UR - http://hdl.handle.net/11427/8041 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/8041
dc.identifier.vancouvercitationPantelis E. Cognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital population. [Thesis]. University of Cape Town ,Faculty of Humanities ,Department of Psychology, 2005 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/8041en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Psychologyen_ZA
dc.publisher.facultyFaculty of Humanitiesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPsychological Researchen_ZA
dc.subject.otherIncludes bibliographical references (leaves 54-63).en_ZA
dc.titleCognitive outcome of aneurysmal subarachnoid haemorrhage after clipping or coiling : a comparative post intervention study in a hospital populationen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMAen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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