Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa

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dc.contributor.authorReuter, Anja
dc.contributor.authorBeko, Buci
dc.contributor.authorMemani, Boniwe
dc.contributor.authorFurin, Jennifer
dc.contributor.authorDaniels, Johnny
dc.contributor.authorRodriguez, Erickmar
dc.contributor.authorReuter, Hermann
dc.contributor.authorWeich, Lize
dc.contributor.authorIsaakidis, Petros
dc.contributor.authorvon der Heyden, Erin
dc.contributor.authorKock, Yulene
dc.contributor.authorMohr-Holland, Erika
dc.date.accessioned2022-04-09T17:29:48Z
dc.date.available2022-04-09T17:29:48Z
dc.date.issued2022-01-31
dc.date.updated2022-02-24T14:50:23Z
dc.description.abstractSubstance use (SU) is associated with poor rifampicin-resistant tuberculosis (RR-TB) treatment outcomes. In 2017, a SBIRT (SU screening-brief intervention-referral to treatment) was integrated into routine RR-TB care in Khayelitsha, South Africa. This was a retrospective study of persons with RR-TB who were screened for SU between 1 July 2018 and 30 September 2020 using the ASSIST (Alcohol, Smoking and Substance Involvement Screening Test). Here we describe outcomes from this program. Persons scoring moderate/high risk received a brief intervention and referral to treatment. Overall, 333 persons were initiated on RR-TB treatment; 38% (<i>n</i> = 128) were screened for SU. Of those, 88% (<i>n</i> = 113/128) reported SU; 65% (<i>n</i> = 83/128) had moderate/high risk SU. Eighty percent (<i>n</i> = 103/128) reported alcohol use, of whom 52% (<i>n</i> = 54/103) reported moderate/high risk alcohol use. Seventy-seven persons were screened for SU within &le;2 months of RR-TB treatment initiation, of whom 69%, 12%, and 12% had outcomes of treatment success, loss to follow-up and death, respectively. Outcomes did not differ between persons with no/low risk and moderate/high risk SU or based on the receipt of naltrexone (<i>p</i> &gt; 0.05). SU was common among persons with RR-TB; there is a need for interventions to address this co-morbidity as part of &ldquo;person-centered care&rdquo;. Integrated, holistic care is needed at the community level to address unique challenges of persons with RR-TB and SU.en_US
dc.identifierdoi: 10.3390/tropicalmed7020021
dc.identifier.apacitationReuter, A., Beko, B., Memani, B., Furin, J., Daniels, J., Rodriguez, E., ... Mohr-Holland, E. (2022). Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa. <i>Tropical Medicine and Infectious Disease</i>, 7(2), 21. http://hdl.handle.net/11427/36321en_ZA
dc.identifier.chicagocitationReuter, Anja, Buci Beko, Boniwe Memani, Jennifer Furin, Johnny Daniels, Erickmar Rodriguez, Hermann Reuter, et al "Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa." <i>Tropical Medicine and Infectious Disease</i> 7, 2. (2022): 21. http://hdl.handle.net/11427/36321en_ZA
dc.identifier.citationReuter, A., Beko, B., Memani, B., Furin, J., Daniels, J., Rodriguez, E., Reuter, H. & Weich, L. et al. 2022. Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa. <i>Tropical Medicine and Infectious Disease.</i> 7(2):21. http://hdl.handle.net/11427/36321en_ZA
dc.identifier.ris TY - Journal Article AU - Reuter, Anja AU - Beko, Buci AU - Memani, Boniwe AU - Furin, Jennifer AU - Daniels, Johnny AU - Rodriguez, Erickmar AU - Reuter, Hermann AU - Weich, Lize AU - Isaakidis, Petros AU - von der Heyden, Erin AU - Kock, Yulene AU - Mohr-Holland, Erika AB - Substance use (SU) is associated with poor rifampicin-resistant tuberculosis (RR-TB) treatment outcomes. In 2017, a SBIRT (SU screening-brief intervention-referral to treatment) was integrated into routine RR-TB care in Khayelitsha, South Africa. This was a retrospective study of persons with RR-TB who were screened for SU between 1 July 2018 and 30 September 2020 using the ASSIST (Alcohol, Smoking and Substance Involvement Screening Test). Here we describe outcomes from this program. Persons scoring moderate/high risk received a brief intervention and referral to treatment. Overall, 333 persons were initiated on RR-TB treatment; 38% (<i>n</i> = 128) were screened for SU. Of those, 88% (<i>n</i> = 113/128) reported SU; 65% (<i>n</i> = 83/128) had moderate/high risk SU. Eighty percent (<i>n</i> = 103/128) reported alcohol use, of whom 52% (<i>n</i> = 54/103) reported moderate/high risk alcohol use. Seventy-seven persons were screened for SU within &le;2 months of RR-TB treatment initiation, of whom 69%, 12%, and 12% had outcomes of treatment success, loss to follow-up and death, respectively. Outcomes did not differ between persons with no/low risk and moderate/high risk SU or based on the receipt of naltrexone (<i>p</i> &gt; 0.05). SU was common among persons with RR-TB; there is a need for interventions to address this co-morbidity as part of &ldquo;person-centered care&rdquo;. Integrated, holistic care is needed at the community level to address unique challenges of persons with RR-TB and SU. DA - 2022-01-31 DB - OpenUCT DP - University of Cape Town IS - 2 J1 - Tropical Medicine and Infectious Disease LK - https://open.uct.ac.za PY - 2022 T1 - Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa TI - Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa UR - http://hdl.handle.net/11427/36321 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/36321
dc.identifier.vancouvercitationReuter A, Beko B, Memani B, Furin J, Daniels J, Rodriguez E, et al. Implementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africa. Tropical Medicine and Infectious Disease. 2022;7(2):21. http://hdl.handle.net/11427/36321.en_ZA
dc.language.isoenen_US
dc.publisher.departmentPrimary Health Care Directorateen_US
dc.publisher.facultyFaculty of Health Sciencesen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.sourceTropical Medicine and Infectious Diseaseen_US
dc.source.journalissue2en_US
dc.source.journalvolume7en_US
dc.source.pagination21en_US
dc.source.urihttps://www.mdpi.com/journal/tropicalmed
dc.titleImplementing a Substance-Use Screening and Intervention Program for People Living with Rifampicin-Resistant Tuberculosis: Pragmatic Experience from Khayelitsha, South Africaen_US
dc.typeJournal Articleen_US
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