Systems medicine and integrated care to combat chronic noncommunicable diseases

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dc.contributor.authorBousquet, Jeanen_ZA
dc.contributor.authorAnto, Josepen_ZA
dc.contributor.authorSterk, Peteren_ZA
dc.contributor.authorAdcock, Ianen_ZA
dc.contributor.authorChung, Kianen_ZA
dc.contributor.authorRoca, Josepen_ZA
dc.contributor.authorAgusti, Alvaren_ZA
dc.contributor.authorBrightling, Chrisen_ZA
dc.contributor.authorCambon-Thomsen, Anneen_ZA
dc.contributor.authorCesario, Alfredoen_ZA
dc.contributor.authorAbdelhak, Soniaen_ZA
dc.contributor.authorAntonarakis, Stylianosen_ZA
dc.contributor.authorAvignon, Antoineen_ZA
dc.contributor.authorBallabio, Andreaen_ZA
dc.contributor.authorBaraldi, Eugenioen_ZA
dc.date.accessioned2015-11-11T12:02:45Z
dc.date.available2015-11-11T12:02:45Z
dc.date.issued2011en_ZA
dc.description.abstractWe propose an innovative, integrated, cost-effective health system to combat major non-communicable diseases (NCDs), including cardiovascular, chronic respiratory, metabolic, rheumatologic and neurologic disorders and cancers, which together are the predominant health problem of the 21st century. This proposed holistic strategy involves comprehensive patient-centered integrated care and multi-scale, multi-modal and multi-level systems approaches to tackle NCDs as a common group of diseases. Rather than studying each disease individually, it will take into account their intertwined gene-environment, socio-economic interactions and co-morbidities that lead to individual-specific complex phenotypes. It will implement a road map for predictive, preventive, personalized and participatory (P4) medicine based on a robust and extensive knowledge management infrastructure that contains individual patient information. It will be supported by strategic partnerships involving all stakeholders, including general practitioners associated with patient-centered care. This systems medicine strategy, which will take a holistic approach to disease, is designed to allow the results to be used globally, taking into account the needs and specificities of local economies and health systems.en_ZA
dc.identifier.apacitationBousquet, J., Anto, J., Sterk, P., Adcock, I., Chung, K., Roca, J., ... Baraldi, E. (2011). Systems medicine and integrated care to combat chronic noncommunicable diseases. <i>Genome Medicine</i>, http://hdl.handle.net/11427/14897en_ZA
dc.identifier.chicagocitationBousquet, Jean, Josep Anto, Peter Sterk, Ian Adcock, Kian Chung, Josep Roca, Alvar Agusti, et al "Systems medicine and integrated care to combat chronic noncommunicable diseases." <i>Genome Medicine</i> (2011) http://hdl.handle.net/11427/14897en_ZA
dc.identifier.citationBousquet, J., Anto, J. M., Sterk, P. J., Adcock, I. M., Chung, K. F., Roca, J., ... & Simon, H. U. (2011). Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome medicine, 3(7), 1-12.en_ZA
dc.identifier.ris TY - Journal Article AU - Bousquet, Jean AU - Anto, Josep AU - Sterk, Peter AU - Adcock, Ian AU - Chung, Kian AU - Roca, Josep AU - Agusti, Alvar AU - Brightling, Chris AU - Cambon-Thomsen, Anne AU - Cesario, Alfredo AU - Abdelhak, Sonia AU - Antonarakis, Stylianos AU - Avignon, Antoine AU - Ballabio, Andrea AU - Baraldi, Eugenio AB - We propose an innovative, integrated, cost-effective health system to combat major non-communicable diseases (NCDs), including cardiovascular, chronic respiratory, metabolic, rheumatologic and neurologic disorders and cancers, which together are the predominant health problem of the 21st century. This proposed holistic strategy involves comprehensive patient-centered integrated care and multi-scale, multi-modal and multi-level systems approaches to tackle NCDs as a common group of diseases. Rather than studying each disease individually, it will take into account their intertwined gene-environment, socio-economic interactions and co-morbidities that lead to individual-specific complex phenotypes. It will implement a road map for predictive, preventive, personalized and participatory (P4) medicine based on a robust and extensive knowledge management infrastructure that contains individual patient information. It will be supported by strategic partnerships involving all stakeholders, including general practitioners associated with patient-centered care. This systems medicine strategy, which will take a holistic approach to disease, is designed to allow the results to be used globally, taking into account the needs and specificities of local economies and health systems. DA - 2011 DB - OpenUCT DO - 10.1186/gm259 DP - University of Cape Town J1 - Genome Medicine LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Systems medicine and integrated care to combat chronic noncommunicable diseases TI - Systems medicine and integrated care to combat chronic noncommunicable diseases UR - http://hdl.handle.net/11427/14897 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/14897
dc.identifier.urihttp://dx.doi.org/10.1186/gm259
dc.identifier.vancouvercitationBousquet J, Anto J, Sterk P, Adcock I, Chung K, Roca J, et al. Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Medicine. 2011; http://hdl.handle.net/11427/14897.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2011 BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceGenome Medicineen_ZA
dc.source.urihttp://www.genomemedicine.com/en_ZA
dc.subject.otherP4 Medicineen_ZA
dc.subject.otherChronic NCDsen_ZA
dc.subject.otherSystem Medicineen_ZA
dc.subject.otherCommunity Health Teamen_ZA
dc.subject.otherPrimary Care Clinicianen_ZA
dc.subject.otherBiomass Fuelen_ZA
dc.titleSystems medicine and integrated care to combat chronic noncommunicable diseasesen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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