Response: Selective serotin reputake inhibitors in children and adolescents
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2006
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South African Medical Journal
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University of Cape Town
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Abstract
The introduction of the selective serotonin reuptake inhibitors (SSRIs) was widely viewed as an important advance in clinical psychopharmacology, not only because of their broad-spectrum efficacy but also because of their tolerability and safety advantages, particularly compared with the older tricyclic antidepressants (TCAs) and monoamine oxide inhibitors (MAOIs). Subsequently there has been considerable controversy about this class of agents, partly because of concerns about the extent to which they have been injudiciously prescribed for ‘cosmetic’ problems rather than for genuine psychopathology,1 and partly because of concerns regarding their adverse effects. Most recently, attention has been paid to the appropriate use of SSRIs in children and adolescents.
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Hawkridge, S., Seedat, S., Emsley, R., Carey, P., & Stein, D. (2006). Selective serotonin reuptake inhibitors in children and adolescents. South African Medical Journal, 96(2), 82.