A retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Town

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dc.contributor.advisorMotsohi, Tsepoen_ZA
dc.contributor.authorEngelbrecht, Alida Men_ZA
dc.date.accessioned2016-07-27T10:23:34Z
dc.date.available2016-07-27T10:23:34Z
dc.date.issued2016en_ZA
dc.description.abstractThe implementation of 'Option B+' has increased uptake and access to antiretroviral (ART) care. However, growing concerns exist regarding retention, especially once vertical transmission risk ceases. Considering the importance of adherence to achieve virological suppression and avoid resistance research on retention is crucial. This study compares the retention of women initiated on 'Option B+' to that of women initiating ART for their own health. Additionally possible predictors of loss to follow-up (LTFU) were explored. Women initiating ART between 1 April and 31 August 2013 were allocated to either the pregnant (n=228) or non-pregnant (n=177) cohort. Retrospective review of electronic recordkeeping systems and patient folders measured retention up to 15 months after ART initiation. Demographic data was captured to explore predictors of LTFU. To avoid outcome bias with participants transferred out, analysis included a 'worst case' scenario assuming LTFU of all these participants and a 'best case' scenario assuming continued retention in care.en_ZA
dc.identifier.apacitationEngelbrecht, A. M. (2016). <i>A retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Town</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine. Retrieved from http://hdl.handle.net/11427/20857en_ZA
dc.identifier.chicagocitationEngelbrecht, Alida M. <i>"A retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Town."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine, 2016. http://hdl.handle.net/11427/20857en_ZA
dc.identifier.citationEngelbrecht, A. 2016. A retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Town. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Engelbrecht, Alida M AB - The implementation of 'Option B+' has increased uptake and access to antiretroviral (ART) care. However, growing concerns exist regarding retention, especially once vertical transmission risk ceases. Considering the importance of adherence to achieve virological suppression and avoid resistance research on retention is crucial. This study compares the retention of women initiated on 'Option B+' to that of women initiating ART for their own health. Additionally possible predictors of loss to follow-up (LTFU) were explored. Women initiating ART between 1 April and 31 August 2013 were allocated to either the pregnant (n=228) or non-pregnant (n=177) cohort. Retrospective review of electronic recordkeeping systems and patient folders measured retention up to 15 months after ART initiation. Demographic data was captured to explore predictors of LTFU. To avoid outcome bias with participants transferred out, analysis included a 'worst case' scenario assuming LTFU of all these participants and a 'best case' scenario assuming continued retention in care. DA - 2016 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2016 T1 - A retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Town TI - A retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Town UR - http://hdl.handle.net/11427/20857 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/20857
dc.identifier.vancouvercitationEngelbrecht AM. A retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Town. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine, 2016 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/20857en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Public Health and Family Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherFamily Medicineen_ZA
dc.titleA retrospective cohort study: The retention in care of HIV positive pregnant and breastfeeding patients universally initiated on lifelong ART ('OptionB+') in the Klipfontein/Mitchells Plain substructure in Cape Townen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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