Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey

dc.contributor.advisorCourtright, Paul
dc.contributor.authorMwangi, Grace Wangari
dc.date.accessioned2019-05-15T09:57:33Z
dc.date.available2019-05-15T09:57:33Z
dc.date.issued2019
dc.date.updated2019-05-13T13:39:32Z
dc.description.abstractBackground High incidence of post-operative trichiasis and other poor outcomes after surgery in most trachoma-endemic settings poses a major challenge to global elimination of trachoma. This systematic review aimed to assess the incidence of post-operative trichiasis and other poor outcomes of trichiasis surgery in Africa, based on findings of observational and interventional studies. Search methods We searched PubMed, Academic Search Premier, Africa-Wide Information, CINAHL and Health Source Nursing through EBSCOhost, Web of Science [all databases], and Cochrane Central Register of Controlled Trials for relevant studies on the subject. We also searched the reference lists of included studies to identify further potentially relevant studies. We included all observational and interventional studies that measured post-operative trichiasis as one of the primary outcomes. Only studies conducted in Africa were included in this review. Data collection and analysis Two reviewers independently screened the titles and abstracts, selected and assessed the articles for inclusion in this review. Any disagreements were resolved through discussion or by consulting a third reviewer. Where necessary, the corresponding authors of included studies were contacted to provide any missing data. Our primary outcome was post-operative trichiasis, which was defined as any eyelash touching the globe at different time points after surgery. Main results Thirty-five studies, including 12,943 participants, met the inclusion criteria. A number of the studies included in this review utilized the same data to measure the incidence of post-operative trichiasis and other poor outcomes over different follow-up periods. Overall, a review of the included studies revealed a pattern of high incidence of post-operative trichiasis and other poor outcomes ranging from 2.3 at 6 weeks to 65% at 7 years. This incidence varied by type of study design, surgical procedure and technique used as well as the follow up period among other factors.
dc.identifier.apacitationMwangi, G. W. (2019). <i>Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey</i>. (). ,Faculty of Health Sciences ,Division of General Surgery. Retrieved from http://hdl.handle.net/11427/30108en_ZA
dc.identifier.chicagocitationMwangi, Grace Wangari. <i>"Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey."</i> ., ,Faculty of Health Sciences ,Division of General Surgery, 2019. http://hdl.handle.net/11427/30108en_ZA
dc.identifier.citationMwangi, G.W. 2019. Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey. . ,Faculty of Health Sciences ,Division of General Surgery. http://hdl.handle.net/11427/30108en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Mwangi, Grace Wangari AB - Background High incidence of post-operative trichiasis and other poor outcomes after surgery in most trachoma-endemic settings poses a major challenge to global elimination of trachoma. This systematic review aimed to assess the incidence of post-operative trichiasis and other poor outcomes of trichiasis surgery in Africa, based on findings of observational and interventional studies. Search methods We searched PubMed, Academic Search Premier, Africa-Wide Information, CINAHL and Health Source Nursing through EBSCOhost, Web of Science [all databases], and Cochrane Central Register of Controlled Trials for relevant studies on the subject. We also searched the reference lists of included studies to identify further potentially relevant studies. We included all observational and interventional studies that measured post-operative trichiasis as one of the primary outcomes. Only studies conducted in Africa were included in this review. Data collection and analysis Two reviewers independently screened the titles and abstracts, selected and assessed the articles for inclusion in this review. Any disagreements were resolved through discussion or by consulting a third reviewer. Where necessary, the corresponding authors of included studies were contacted to provide any missing data. Our primary outcome was post-operative trichiasis, which was defined as any eyelash touching the globe at different time points after surgery. Main results Thirty-five studies, including 12,943 participants, met the inclusion criteria. A number of the studies included in this review utilized the same data to measure the incidence of post-operative trichiasis and other poor outcomes over different follow-up periods. Overall, a review of the included studies revealed a pattern of high incidence of post-operative trichiasis and other poor outcomes ranging from 2.3 at 6 weeks to 65% at 7 years. This incidence varied by type of study design, surgical procedure and technique used as well as the follow up period among other factors. DA - 2019 DB - OpenUCT DP - University of Cape Town KW - post-operative trichiasis, trachoma, trichiasis surgery LK - https://open.uct.ac.za PY - 2019 T1 - Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey TI - Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey UR - http://hdl.handle.net/11427/30108 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/30108
dc.identifier.vancouvercitationMwangi GW. Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey. []. ,Faculty of Health Sciences ,Division of General Surgery, 2019 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/30108en_ZA
dc.language.rfc3066eng
dc.publisher.departmentDivision of General Surgery
dc.publisher.facultyFaculty of Health Sciences
dc.subjectpost-operative trichiasis, trachoma, trichiasis surgery
dc.titlePost-operative Trachomatous Trichiasis in Africa: a systematic review and online survey
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMPH
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