Apnoea of prematurity - discontinuation of methylxanthines in a resource-limited setting
| dc.contributor.author | Tooke, L J | |
| dc.contributor.author | Browde, K | |
| dc.contributor.author | Harrison, M C | |
| dc.date.accessioned | 2016-04-29T13:30:20Z | |
| dc.date.available | 2016-04-29T13:30:20Z | |
| dc.date.issued | 2013 | |
| dc.date.updated | 2016-04-29T13:26:39Z | |
| dc.description.abstract | Background: Methylxanthines such as caffeine have been proven to reduce apnoea of prematurity and are often discontinued at 35 weeks’ corrected gestational age (GA). Objective. To ascertain whether a caffeine protocol based on international guidelines is applicable in our setting, where GA is often uncertain. Methods: A prospective folder review was undertaken of all premature infants discharged home over a 2-month period. Results: Fifty-five babies were included. All babies born at less than 35 weeks’ GA were correctly started on caffeine as per protocol. GA was assigned in 85.5% of cases by Ballard scoring and in 14.5% from antenatal ultrasound findings. Caffeine was discontinued before 35 weeks in 54.5%. Discussion: The main reason for discontinuing caffeine early was the baby’s ability to feed satisfactorily, a demonstration of physiological maturity. As feeding behaviours mature significantly between 33 and 36 weeks, the ability to feed may be a good indication that caffeine therapy can be stopped. | en_ZA |
| dc.identifier | http://dx.doi.org/10.7196/SAJCH.630 | |
| dc.identifier.apacitation | Tooke, L. J., Browde, K., & Harrison, M. C. (2013). Apnoea of prematurity - discontinuation of methylxanthines in a resource-limited setting. <i>South African Journal of Child Health</i>, http://hdl.handle.net/11427/19340 | en_ZA |
| dc.identifier.chicagocitation | Tooke, L J, K Browde, and M C Harrison "Apnoea of prematurity - discontinuation of methylxanthines in a resource-limited setting." <i>South African Journal of Child Health</i> (2013) http://hdl.handle.net/11427/19340 | en_ZA |
| dc.identifier.citation | Tooke, L. J., Browde, K., & Harrison, M. C. (2013). Apnoea of prematurity–discontinuation of methylxanthines in a resource-limited setting. South African Journal of Child Health, 7(4), 146-147. | en_ZA |
| dc.identifier.issn | 1994-3032 | en_ZA |
| dc.identifier.ris | TY - Journal Article AU - Tooke, L J AU - Browde, K AU - Harrison, M C AB - Background: Methylxanthines such as caffeine have been proven to reduce apnoea of prematurity and are often discontinued at 35 weeks’ corrected gestational age (GA). Objective. To ascertain whether a caffeine protocol based on international guidelines is applicable in our setting, where GA is often uncertain. Methods: A prospective folder review was undertaken of all premature infants discharged home over a 2-month period. Results: Fifty-five babies were included. All babies born at less than 35 weeks’ GA were correctly started on caffeine as per protocol. GA was assigned in 85.5% of cases by Ballard scoring and in 14.5% from antenatal ultrasound findings. Caffeine was discontinued before 35 weeks in 54.5%. Discussion: The main reason for discontinuing caffeine early was the baby’s ability to feed satisfactorily, a demonstration of physiological maturity. As feeding behaviours mature significantly between 33 and 36 weeks, the ability to feed may be a good indication that caffeine therapy can be stopped. DA - 2013 DB - OpenUCT DP - University of Cape Town J1 - South African Journal of Child Health LK - https://open.uct.ac.za PB - University of Cape Town PY - 2013 SM - 1994-3032 T1 - Apnoea of prematurity - discontinuation of methylxanthines in a resource-limited setting TI - Apnoea of prematurity - discontinuation of methylxanthines in a resource-limited setting UR - http://hdl.handle.net/11427/19340 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/19340 | |
| dc.identifier.uri | http://sajch.org.za/index.php/SAJCH/article/view/630 | |
| dc.identifier.vancouvercitation | Tooke LJ, Browde K, Harrison MC. Apnoea of prematurity - discontinuation of methylxanthines in a resource-limited setting. South African Journal of Child Health. 2013; http://hdl.handle.net/11427/19340. | en_ZA |
| dc.language | eng | en_ZA |
| dc.publisher | Health and Medical Publishing Group | en_ZA |
| dc.publisher.department | Division of Neonatology | en_ZA |
| dc.publisher.faculty | Faculty of Health Sciences | en_ZA |
| dc.publisher.institution | University of Cape Town | |
| dc.rights | Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | en_ZA |
| dc.source | South African Journal of Child Health | en_ZA |
| dc.source.uri | http://www.sajch.org.za/index.php/SAJCH | |
| dc.subject.other | prematurity | |
| dc.subject.other | apnoea | |
| dc.subject.other | caffeine | |
| dc.subject.other | methylxanthines | |
| dc.title | Apnoea of prematurity - discontinuation of methylxanthines in a resource-limited setting | en_ZA |
| dc.type | Journal Article | en_ZA |
| uct.type.filetype | Text | |
| uct.type.filetype | Image | |
| uct.type.publication | Research | en_ZA |
| uct.type.resource | Article | en_ZA |