Investigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapy

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dc.contributor.advisorPillay, Tahir Sen_ZA
dc.contributor.authorOmar, Feirdozen_ZA
dc.date.accessioned2014-07-28T08:14:07Z
dc.date.available2014-07-28T08:14:07Z
dc.date.issued2010en_ZA
dc.description.abstractThis project aims to investigate the role of multimeric (high molecular weight) adiponectin in the development of metabolic disease resulting from anti-retroviral therapy. Specifically, the aim is to quantify the circulating levels of both total and high molecular weight (HMW) adiponectin and to establish whether a link exists between HMW adiponectin levels and susceptibility to HIV-induced lipodystrophy. Although total adiponectin levels have been shown to be significantly reduced in patients with HIVinduced lipodystrophy, there is no information on whether HMW adiponectin, which appears to be the most biologically active form of adiponectin, is altered in HAARTinduced lipodystrophy, and whether patients with low levels of the HMW form are more susceptible to lipodystrophy.en_ZA
dc.identifier.apacitationOmar, F. (2010). <i>Investigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapy</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Chemical Pathology. Retrieved from http://hdl.handle.net/11427/2699en_ZA
dc.identifier.chicagocitationOmar, Feirdoz. <i>"Investigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapy."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Chemical Pathology, 2010. http://hdl.handle.net/11427/2699en_ZA
dc.identifier.citationOmar, F. 2010. Investigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapy. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Omar, Feirdoz AB - This project aims to investigate the role of multimeric (high molecular weight) adiponectin in the development of metabolic disease resulting from anti-retroviral therapy. Specifically, the aim is to quantify the circulating levels of both total and high molecular weight (HMW) adiponectin and to establish whether a link exists between HMW adiponectin levels and susceptibility to HIV-induced lipodystrophy. Although total adiponectin levels have been shown to be significantly reduced in patients with HIVinduced lipodystrophy, there is no information on whether HMW adiponectin, which appears to be the most biologically active form of adiponectin, is altered in HAARTinduced lipodystrophy, and whether patients with low levels of the HMW form are more susceptible to lipodystrophy. DA - 2010 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2010 T1 - Investigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapy TI - Investigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapy UR - http://hdl.handle.net/11427/2699 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/2699
dc.identifier.vancouvercitationOmar F. Investigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapy. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Chemical Pathology, 2010 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/2699en_ZA
dc.language.isoeng
dc.publisher.departmentDivision of Chemical Pathologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherChemical Pathologyen_ZA
dc.titleInvestigation of High Molecular weight adiponectin in HIV -Infected patients on antiretroviral therapyen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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