SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study

Simple item page
dc.contributor.authorArendse, Tracy
dc.contributor.authorCowper, Beverley
dc.contributor.authorCohen, Cheryl
dc.contributor.authorMasha, Maureen
dc.contributor.authorTempia, Stefano
dc.contributor.authorLegodu, Civil
dc.contributor.authorSingh, Sandhya
dc.contributor.authorRatau, Tebogo
dc.contributor.authorGeffen, Leon
dc.contributor.authorHeymans, Ansie
dc.contributor.authorCoetzer, Dane
dc.contributor.authorBlumberg, Lucille
dc.contributor.authorJassat, Waasila
dc.date.accessioned2022-09-13T13:45:16Z
dc.date.available2022-09-13T13:45:16Z
dc.date.issued2022-05-24
dc.date.updated2022-05-30T09:16:11Z
dc.description.abstractBackground Globally, long-term care facilities (LTCFs) experienced a large burden of deaths during the COVID-19 pandemic. The study aimed to describe the temporal trends as well as the characteristics and risk factors for mortality among residents and staff who tested positive for SARS-CoV-2 in selected LTCFs across South Africa. Method We analysed data reported to the DATCOV sentinel surveillance system by 45 LTCFs. Outbreaks in LTCFs were defined as large if more than one-third of residents and staff had been infected or there were more than 20 epidemiologically linked cases. Multivariable logistic regression was used to assess risk factors for mortality amongst LTCF residents. Results A total of 2324 SARS-CoV-2 cases were reported from 5 March 2020 through 31 July 2021; 1504 (65%) were residents and 820 (35%) staff. Among LTCFs, 6 reported sporadic cases and 39 experienced outbreaks. Of those reporting outbreaks, 10 (26%) reported one and 29 (74%) reported more than one outbreak. There were 48 (66.7%) small outbreaks and 24 (33.3%) large outbreaks reported. There were 30 outbreaks reported in the first wave, 21 in the second wave and 15 in the third wave, with 6 outbreaks reporting between waves. There were 1259 cases during the first COVID-19 wave, 362 during the second wave, and 299 during the current third wave. The case fatality ratio was 9% (138/1504) among residents and 0.5% (4/820) among staff. On multivariable analysis, factors associated with SARS-CoV-2 mortality among LTCF residents were age 40–59 years, 60–79 years and ≥ 80 years compared to < 40 years and being a resident in a LTCF in Free State or Northern Cape compared to Western Cape. Compared to pre-wave 1, there was a decreased risk of mortality in wave 1, post-wave 1, wave 2, post-wave 2 and wave 3. Conclusion The analysis of SARS-CoV-2 cases in sentinel LTCFs in South Africa points to an encouraging trend of decreasing numbers of outbreaks, cases and risk for mortality since the first wave. LTCFs are likely to have learnt from international experience and adopted national protocols, which include improved measures to limit transmission and administer early and appropriate clinical care.en_US
dc.identifier.apacitationArendse, T., Cowper, B., Cohen, C., Masha, M., Tempia, S., Legodu, C., ... Jassat, W. (2022). SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study. <i>BMC Public Health</i>, 22(1), 1035. http://hdl.handle.net/11427/36806en_ZA
dc.identifier.chicagocitationArendse, Tracy, Beverley Cowper, Cheryl Cohen, Maureen Masha, Stefano Tempia, Civil Legodu, Sandhya Singh, et al "SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study." <i>BMC Public Health</i> 22, 1. (2022): 1035. http://hdl.handle.net/11427/36806en_ZA
dc.identifier.citationArendse, T., Cowper, B., Cohen, C., Masha, M., Tempia, S., Legodu, C., Singh, S. & Ratau, T. et al. 2022. SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study. <i>BMC Public Health.</i> 22(1):1035. http://hdl.handle.net/11427/36806en_ZA
dc.identifier.ris TY - Journal Article AU - Arendse, Tracy AU - Cowper, Beverley AU - Cohen, Cheryl AU - Masha, Maureen AU - Tempia, Stefano AU - Legodu, Civil AU - Singh, Sandhya AU - Ratau, Tebogo AU - Geffen, Leon AU - Heymans, Ansie AU - Coetzer, Dane AU - Blumberg, Lucille AU - Jassat, Waasila AB - Background Globally, long-term care facilities (LTCFs) experienced a large burden of deaths during the COVID-19 pandemic. The study aimed to describe the temporal trends as well as the characteristics and risk factors for mortality among residents and staff who tested positive for SARS-CoV-2 in selected LTCFs across South Africa. Method We analysed data reported to the DATCOV sentinel surveillance system by 45 LTCFs. Outbreaks in LTCFs were defined as large if more than one-third of residents and staff had been infected or there were more than 20 epidemiologically linked cases. Multivariable logistic regression was used to assess risk factors for mortality amongst LTCF residents. Results A total of 2324 SARS-CoV-2 cases were reported from 5 March 2020 through 31 July 2021; 1504 (65%) were residents and 820 (35%) staff. Among LTCFs, 6 reported sporadic cases and 39 experienced outbreaks. Of those reporting outbreaks, 10 (26%) reported one and 29 (74%) reported more than one outbreak. There were 48 (66.7%) small outbreaks and 24 (33.3%) large outbreaks reported. There were 30 outbreaks reported in the first wave, 21 in the second wave and 15 in the third wave, with 6 outbreaks reporting between waves. There were 1259 cases during the first COVID-19 wave, 362 during the second wave, and 299 during the current third wave. The case fatality ratio was 9% (138/1504) among residents and 0.5% (4/820) among staff. On multivariable analysis, factors associated with SARS-CoV-2 mortality among LTCF residents were age 40–59 years, 60–79 years and ≥ 80 years compared to < 40 years and being a resident in a LTCF in Free State or Northern Cape compared to Western Cape. Compared to pre-wave 1, there was a decreased risk of mortality in wave 1, post-wave 1, wave 2, post-wave 2 and wave 3. Conclusion The analysis of SARS-CoV-2 cases in sentinel LTCFs in South Africa points to an encouraging trend of decreasing numbers of outbreaks, cases and risk for mortality since the first wave. LTCFs are likely to have learnt from international experience and adopted national protocols, which include improved measures to limit transmission and administer early and appropriate clinical care. DA - 2022-05-24 DB - OpenUCT DP - University of Cape Town IS - 1 J1 - BMC Public Health KW - Long term care facilities KW - Outbreak KW - Case fatality ratio KW - SARS-CoV-2 KW - Residents KW - Staff LK - https://open.uct.ac.za PY - 2022 T1 - SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study TI - SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study UR - http://hdl.handle.net/11427/36806 ER - en_ZA
dc.identifier.urihttps://doi.org/10.1186/s12889-022-13403-6
dc.identifier.urihttp://hdl.handle.net/11427/36806
dc.identifier.vancouvercitationArendse T, Cowper B, Cohen C, Masha M, Tempia S, Legodu C, et al. SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study. BMC Public Health. 2022;22(1):1035. http://hdl.handle.net/11427/36806.en_ZA
dc.language.isoenen_US
dc.language.rfc3066en
dc.publisher.departmentDepartment of Medicineen_US
dc.publisher.facultyFaculty of Health Sciencesen_US
dc.rights.holderThe Author(s)
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.sourceBMC Public Healthen_US
dc.source.journalissue1en_US
dc.source.journalvolume22en_US
dc.source.pagination1035en_US
dc.subjectLong term care facilitiesen_US
dc.subjectOutbreaken_US
dc.subjectCase fatality ratioen_US
dc.subjectSARS-CoV-2en_US
dc.subjectResidentsen_US
dc.subjectStaffen_US
dc.titleSARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort studyen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
12889_2022_Article_13403.pdf
Size:
1.29 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
0 B
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal Articles