Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study

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dc.contributor.authorHowells, Fleuren_ZA
dc.contributor.authorIves-Deliperi, Victoriaen_ZA
dc.contributor.authorHorn, Neilen_ZA
dc.contributor.authorStein, Danen_ZA
dc.date.accessioned2015-11-18T04:02:10Z
dc.date.available2015-11-18T04:02:10Z
dc.date.issued2012en_ZA
dc.description.abstractBACKGROUND: Cognitive processing in Bipolar Disorder is characterized by a number of attentional abnormalities. Mindfulness Based Cognitive Therapy combines mindfulness meditation, a form of attentional training, along with aspects of cognitive therapy, and may improve attentional dysfunction in bipolar disorder patients. METHODS: 12 euthymic BD patients and 9 control participants underwent record of electroencephalography (EEG, band frequency analysis) during resting states (eyes open, eyes closed) and during the completion of a continuous performance task (A-X version, EEG event-related potential (ERP) wave component analysis). The individuals with BD completed an 8-week MBCT intervention and record of EEG was repeated. RESULTS: (1) Brain activity, individuals with BD showed significantly decreased theta band power, increased beta band power, and decreased theta/beta ratios during the resting state, eyes closed, for frontal and cingulate cortices. Post MBCT intervention improvement over the right frontal cortex was seen in the individuals with BD, as beta band power decreased. (2) Brain activation, individuals with BD showed a significant P300-like wave form over the frontal cortex during the cue. Post MBCT intervention the P300-like waveform was significantly attenuated over the frontal cortex. CONCLUSIONS: Individuals with BD show decreased attentional readiness and activation of non-relevant information processing during attentional processes. These data are the first that show, MBCT in BD improved attentional readiness, and attenuated activation of non-relevant information processing during attentional processes.en_ZA
dc.identifier.apacitationHowells, F., Ives-Deliperi, V., Horn, N., & Stein, D. (2012). Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study. <i>BMC Psychiatry</i>, http://hdl.handle.net/11427/15100en_ZA
dc.identifier.chicagocitationHowells, Fleur, Victoria Ives-Deliperi, Neil Horn, and Dan Stein "Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study." <i>BMC Psychiatry</i> (2012) http://hdl.handle.net/11427/15100en_ZA
dc.identifier.citationHowells, F. M., Ives-Deliperi, V. L., Horn, N. R., & Stein, D. J. (2012). Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study. BMC psychiatry, 12(1), 15.en_ZA
dc.identifier.ris TY - Journal Article AU - Howells, Fleur AU - Ives-Deliperi, Victoria AU - Horn, Neil AU - Stein, Dan AB - BACKGROUND: Cognitive processing in Bipolar Disorder is characterized by a number of attentional abnormalities. Mindfulness Based Cognitive Therapy combines mindfulness meditation, a form of attentional training, along with aspects of cognitive therapy, and may improve attentional dysfunction in bipolar disorder patients. METHODS: 12 euthymic BD patients and 9 control participants underwent record of electroencephalography (EEG, band frequency analysis) during resting states (eyes open, eyes closed) and during the completion of a continuous performance task (A-X version, EEG event-related potential (ERP) wave component analysis). The individuals with BD completed an 8-week MBCT intervention and record of EEG was repeated. RESULTS: (1) Brain activity, individuals with BD showed significantly decreased theta band power, increased beta band power, and decreased theta/beta ratios during the resting state, eyes closed, for frontal and cingulate cortices. Post MBCT intervention improvement over the right frontal cortex was seen in the individuals with BD, as beta band power decreased. (2) Brain activation, individuals with BD showed a significant P300-like wave form over the frontal cortex during the cue. Post MBCT intervention the P300-like waveform was significantly attenuated over the frontal cortex. CONCLUSIONS: Individuals with BD show decreased attentional readiness and activation of non-relevant information processing during attentional processes. These data are the first that show, MBCT in BD improved attentional readiness, and attenuated activation of non-relevant information processing during attentional processes. DA - 2012 DB - OpenUCT DO - 10.1186/1471-244X-12-15 DP - University of Cape Town J1 - BMC Psychiatry LK - https://open.uct.ac.za PB - University of Cape Town PY - 2012 T1 - Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study TI - Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study UR - http://hdl.handle.net/11427/15100 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15100
dc.identifier.urihttp://dx.doi.org/10.1186/1471-244X-12-15
dc.identifier.vancouvercitationHowells F, Ives-Deliperi V, Horn N, Stein D. Mindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG study. BMC Psychiatry. 2012; http://hdl.handle.net/11427/15100.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Psychiatry and Mental Healthen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2012 Howells et al; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceBMC Psychiatryen_ZA
dc.source.urihttp://bmcpsychiatry.biomedcentral.com/en_ZA
dc.subject.otherCognitive processingen_ZA
dc.subject.otherBipolar Disorderen_ZA
dc.titleMindfulness based cognitive therapy improves frontal control in bipolar disorder: a pilot EEG studyen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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