A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions
| dc.contributor.advisor | Horn, Neil | |
| dc.contributor.advisor | Williams-Ashman, Peter | |
| dc.contributor.author | Charles, Bhaskaran Nathamaniar | |
| dc.date.accessioned | 2019-02-18T09:16:07Z | |
| dc.date.available | 2019-02-18T09:16:07Z | |
| dc.date.issued | 2018 | |
| dc.date.updated | 2019-02-18T09:00:31Z | |
| dc.description.abstract | Background: The impact on hospitalisations/ relapse rates of utilising long-acting antipsychotic injectable (LAIs) in a South African population suffering from chronic psychotic spectrum mental illness is poorly researched. Aim: To compare the duration and number of hospitalisation episodes 12 and 24 months before and after the initiation of a LAI. Setting: Valkenberg Hospital’s adult acute inpatient psychiatry services. Method: This was a retrospective naturalistic observational mirror-image study. Hospitalisation was utilised as a proxy for relapse. Results: Sixty-one patients were identified for the study. A comparison of the 12 months before LAI initiation to the 12 months following LAI initiation showed a reduction in the number of admissions of 44% (55 to 31), and a reduction in the number of inpatient days of 23% (1892 to 1464). There was a statistically significant reduction in the median number of hospital admissions (p = 0.005) and median inpatient days (p = 0.040). Comparing the 24 months before to the 24 months following LAI initiation, there was a reduction in the number of admissions of 30% (91 to 64) and inpatient days of 4% (3477 to 3355). There was a statistically significant reduction in the median number of hospital admissions (p = 0.014) and a non-statistically significant reduction in median days (p = 0.428). Conclusion: The prescription of a LAI reduced the duration and number of hospital admissions over a 12-month period. After 24 months, there were fewer admissions but no significant reduction in the number of inpatient days. This study supports findings of international mirror-image studies. | |
| dc.identifier.apacitation | Charles, B. N. (2018). <i>A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions</i>. (). University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health. Retrieved from http://hdl.handle.net/11427/29562 | en_ZA |
| dc.identifier.chicagocitation | Charles, Bhaskaran Nathamaniar. <i>"A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions."</i> ., University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health, 2018. http://hdl.handle.net/11427/29562 | en_ZA |
| dc.identifier.citation | Charles, B. 2018. A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions. University of Cape Town. | en_ZA |
| dc.identifier.ris | TY - Thesis / Dissertation AU - Charles, Bhaskaran Nathamaniar AB - Background: The impact on hospitalisations/ relapse rates of utilising long-acting antipsychotic injectable (LAIs) in a South African population suffering from chronic psychotic spectrum mental illness is poorly researched. Aim: To compare the duration and number of hospitalisation episodes 12 and 24 months before and after the initiation of a LAI. Setting: Valkenberg Hospital’s adult acute inpatient psychiatry services. Method: This was a retrospective naturalistic observational mirror-image study. Hospitalisation was utilised as a proxy for relapse. Results: Sixty-one patients were identified for the study. A comparison of the 12 months before LAI initiation to the 12 months following LAI initiation showed a reduction in the number of admissions of 44% (55 to 31), and a reduction in the number of inpatient days of 23% (1892 to 1464). There was a statistically significant reduction in the median number of hospital admissions (p = 0.005) and median inpatient days (p = 0.040). Comparing the 24 months before to the 24 months following LAI initiation, there was a reduction in the number of admissions of 30% (91 to 64) and inpatient days of 4% (3477 to 3355). There was a statistically significant reduction in the median number of hospital admissions (p = 0.014) and a non-statistically significant reduction in median days (p = 0.428). Conclusion: The prescription of a LAI reduced the duration and number of hospital admissions over a 12-month period. After 24 months, there were fewer admissions but no significant reduction in the number of inpatient days. This study supports findings of international mirror-image studies. DA - 2018 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2018 T1 - A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions TI - A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions UR - http://hdl.handle.net/11427/29562 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/29562 | |
| dc.identifier.vancouvercitation | Charles BN. A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions. []. University of Cape Town ,Faculty of Health Sciences ,Department of Psychiatry and Mental Health, 2018 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/29562 | en_ZA |
| dc.language.iso | eng | |
| dc.publisher.department | Department of Psychiatry and Mental Health | |
| dc.publisher.faculty | Faculty of Health Sciences | |
| dc.publisher.institution | University of Cape Town | |
| dc.subject.other | Psychiatry | |
| dc.title | A retrospective observational study of the effectiveness of long acting antipsychotic injectable on hospital admissions | |
| dc.type | Master Thesis | |
| dc.type.qualificationlevel | Masters | |
| dc.type.qualificationname | MMed |