Diagnosing cystic fibrosis in South Africa
| dc.contributor.author | Westwood, Tony | |
| dc.contributor.author | Henderson, Bertram | |
| dc.contributor.author | Ramsay, Michele | |
| dc.date.accessioned | 2017-07-18T13:41:05Z | |
| dc.date.available | 2017-07-18T13:41:05Z | |
| dc.date.issued | 2006 | |
| dc.date.updated | 2016-01-12T10:08:37Z | |
| dc.description.abstract | Cystic fibrosis (CF) occurs in all South Africa’s population groups. While well described in the white and coloured populations, its presence in black African populations is less well known. Recent evidence from the group of CF patients in the Western Cape suggests an incidence of 1 in 3 000 and 1 in 10 300 live births in the white and coloured populations respectively.1 In black South African populations, carrier frequency estimates have been used to project an incidence of 1 in 4 624 live births.2 Further evidence of the presence of CF in these populations is presented in this issue of the Journal. 3 While considering or being aware of the diagnosis is the first step in identifying CF, diagnosing the disease presents challenges at clinical and laboratory levels in South Africa. In simple terms, the diagnosis of CF requires a patient to have suggestive clinical features as well as 2 positive sweat tests and/or 2 identified disease-causing CF transmembrane conductance regulator (CFTR) gene mutations. | |
| dc.identifier | http://dx.doi.org/10.7196/SAMJ.1082 | |
| dc.identifier.apacitation | Westwood, T., Henderson, B., & Ramsay, M. (2006). Diagnosing cystic fibrosis in South Africa. <i>South African Medical Journal</i>, http://hdl.handle.net/11427/24765 | en_ZA |
| dc.identifier.chicagocitation | Westwood, Tony, Bertram Henderson, and Michele Ramsay "Diagnosing cystic fibrosis in South Africa." <i>South African Medical Journal</i> (2006) http://hdl.handle.net/11427/24765 | en_ZA |
| dc.identifier.citation | Westwood, T., Henderson, B., & Ramsay, M. (2006). Diagnosing cystic fibrosis in South Africa. South African Medical Journal, 96(4), 304. | |
| dc.identifier.ris | TY - Journal Article AU - Westwood, Tony AU - Henderson, Bertram AU - Ramsay, Michele AB - Cystic fibrosis (CF) occurs in all South Africa’s population groups. While well described in the white and coloured populations, its presence in black African populations is less well known. Recent evidence from the group of CF patients in the Western Cape suggests an incidence of 1 in 3 000 and 1 in 10 300 live births in the white and coloured populations respectively.1 In black South African populations, carrier frequency estimates have been used to project an incidence of 1 in 4 624 live births.2 Further evidence of the presence of CF in these populations is presented in this issue of the Journal. 3 While considering or being aware of the diagnosis is the first step in identifying CF, diagnosing the disease presents challenges at clinical and laboratory levels in South Africa. In simple terms, the diagnosis of CF requires a patient to have suggestive clinical features as well as 2 positive sweat tests and/or 2 identified disease-causing CF transmembrane conductance regulator (CFTR) gene mutations. DA - 2006 DB - OpenUCT DP - University of Cape Town J1 - South African Medical Journal LK - https://open.uct.ac.za PB - University of Cape Town PY - 2006 T1 - Diagnosing cystic fibrosis in South Africa TI - Diagnosing cystic fibrosis in South Africa UR - http://hdl.handle.net/11427/24765 ER - | en_ZA |
| dc.identifier.uri | http://hdl.handle.net/11427/24765 | |
| dc.identifier.vancouvercitation | Westwood T, Henderson B, Ramsay M. Diagnosing cystic fibrosis in South Africa. South African Medical Journal. 2006; http://hdl.handle.net/11427/24765. | en_ZA |
| dc.language.iso | eng | |
| dc.publisher.department | Division of Paediatric Medicine | en_ZA |
| dc.publisher.faculty | Faculty of Health Sciences | en_ZA |
| dc.publisher.institution | University of Cape Town | |
| dc.source | South African Medical Journal | |
| dc.source.uri | http://www.samj.org.za/index.php/samj | |
| dc.title | Diagnosing cystic fibrosis in South Africa | |
| dc.type | Journal Article | en_ZA |
| uct.type.filetype | Text | |
| uct.type.filetype | Image | |
| uct.type.publication | Research | en_ZA |
| uct.type.resource | Article | en_ZA |