Cognitive outcomes in adults with HIV-associated Tuberculous Meningitis

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dc.contributor.advisorSolms, Mark
dc.contributor.advisorMarais, Suzaan
dc.contributor.advisorGouse, Theta
dc.contributor.advisorBateman, Kathleen
dc.contributor.authorAlbertyn, Christine Herculine
dc.date.accessioned2019-02-07T10:54:28Z
dc.date.available2019-02-07T10:54:28Z
dc.date.issued2017
dc.description.abstractTuberculous meningitis (TBM) is a common cause of meningitis in adults in South Africa (1-3), second only to cryptococcal meningitis in studies of microbiologically confirmed meningitis, and accounting for 28% of cases in one (1). Conventional diagnostic tests for TBM are, however, relatively insensitive, and the true incidence is likely to be underreported. When both microbiological and clinical diagnostic criteria (4) are used in the same setting, the incidence of TBM rose to 57% (3), emerging as the most common cause of meningitis in adults in a district level hospital in the Western Cape. In the setting of high human immunodeficiency virus (HIV) and tuberculosis (TB) prevalence, approximately 88% of patients with definite or probable TBM are co-infected with HIV (3, 5) and six-month mortality in this group approaches 50% (3). Survivors may be left with long-term disability secondary to hydrocephalus, cranial neuropathies, seizures and strokes (6).en_US
dc.identifier.apacitationAlbertyn, C. H. (2017). <i>Cognitive outcomes in adults with HIV-associated Tuberculous Meningitis</i>. (). University of Cape Town ,Faculty of Health Sciences ,Department of Medicine. Retrieved from http://hdl.handle.net/11427/29405en_ZA
dc.identifier.chicagocitationAlbertyn, Christine Herculine. <i>"Cognitive outcomes in adults with HIV-associated Tuberculous Meningitis."</i> ., University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2017. http://hdl.handle.net/11427/29405en_ZA
dc.identifier.citationAlbertyn, C. 2017. Cognitive outcomes in adults with HIV-associated Tuberculous Meningitis. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Albertyn, Christine Herculine AB - Tuberculous meningitis (TBM) is a common cause of meningitis in adults in South Africa (1-3), second only to cryptococcal meningitis in studies of microbiologically confirmed meningitis, and accounting for 28% of cases in one (1). Conventional diagnostic tests for TBM are, however, relatively insensitive, and the true incidence is likely to be underreported. When both microbiological and clinical diagnostic criteria (4) are used in the same setting, the incidence of TBM rose to 57% (3), emerging as the most common cause of meningitis in adults in a district level hospital in the Western Cape. In the setting of high human immunodeficiency virus (HIV) and tuberculosis (TB) prevalence, approximately 88% of patients with definite or probable TBM are co-infected with HIV (3, 5) and six-month mortality in this group approaches 50% (3). Survivors may be left with long-term disability secondary to hydrocephalus, cranial neuropathies, seizures and strokes (6). DA - 2017 DB - OpenUCT DP - University of Cape Town KW - medicine LK - https://open.uct.ac.za PB - University of Cape Town PY - 2017 T1 - Cognitive outcomes in adults with HIV-associated Tuberculous Meningitis TI - Cognitive outcomes in adults with HIV-associated Tuberculous Meningitis UR - http://hdl.handle.net/11427/29405 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/29405
dc.identifier.vancouvercitationAlbertyn CH. Cognitive outcomes in adults with HIV-associated Tuberculous Meningitis. []. University of Cape Town ,Faculty of Health Sciences ,Department of Medicine, 2017 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/29405en_ZA
dc.language.isoenen_US
dc.publisher.departmentDepartment of Medicineen_US
dc.publisher.facultyFaculty of Health Sciencesen_US
dc.publisher.institutionUniversity of Cape Townen_US
dc.subjectmedicineen_US
dc.titleCognitive outcomes in adults with HIV-associated Tuberculous Meningitisen_US
dc.typeThesis
dc.type.qualificationlevelMSc (Med)
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