Growth of luciferase-transfected BCG in whole blood : use of a novel assay to study immune responses to mycobacteria in children
Master Thesis
2003
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University of Cape Town
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Abstract
The existing Bacille Calmette-Guerin (BCG) vaccine offers some protection against TB, but its efficacy varies for unknown reasons. In order to develop an effective vaccine, a comprehensive understanding of protective immunity in adults and children is needed. Studies involving host-pathogen interactions are complex and have been hampered by the slow growth of mycobacterial organisms.
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Includes bibliographical references.
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Tena, N. 2003. Growth of luciferase-transfected BCG in whole blood : use of a novel assay to study immune responses to mycobacteria in children. University of Cape Town.