A study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma

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dc.contributor.advisorGovender, Dhirenen_ZA
dc.contributor.authorPillay, Komalaen_ZA
dc.date.accessioned2014-07-28T14:51:44Z
dc.date.available2014-07-28T14:51:44Z
dc.date.issued2006en_ZA
dc.descriptionIncludes bibliographical references (leaves 64-71).
dc.description.abstractCyclin E and p27 expression is easy to assess in human tissues by standard immunohistochemical techniques. Immunohistochemistry is cost effective, relatively easy to perform and will play more of a role in the future management of cancer. To investigate the role of p27 and cyclin E immunoexpression as a prognostic factor in early breast carcinoma. Cyclin E and p27 immunohistochemistry was performed on sixty six cases of breast carcinoma submtted over a five year period to the Division of Anatomical Pathology, Groote Schuur hospital; Whittaker and Associates; and PathCare. All tumours included in this study were less than 5cm in diameter (pT1 and pT2 stage) and all the patients had wide local excisions peformed. Follow up information was obtained from patient folders in the Department of Radiation Oncology.en_ZA
dc.identifier.apacitationPillay, K. (2006). <i>A study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Division of Anatomical Pathology. Retrieved from http://hdl.handle.net/11427/3085en_ZA
dc.identifier.chicagocitationPillay, Komala. <i>"A study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Division of Anatomical Pathology, 2006. http://hdl.handle.net/11427/3085en_ZA
dc.identifier.citationPillay, K. 2006. A study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Pillay, Komala AB - Cyclin E and p27 expression is easy to assess in human tissues by standard immunohistochemical techniques. Immunohistochemistry is cost effective, relatively easy to perform and will play more of a role in the future management of cancer. To investigate the role of p27 and cyclin E immunoexpression as a prognostic factor in early breast carcinoma. Cyclin E and p27 immunohistochemistry was performed on sixty six cases of breast carcinoma submtted over a five year period to the Division of Anatomical Pathology, Groote Schuur hospital; Whittaker and Associates; and PathCare. All tumours included in this study were less than 5cm in diameter (pT1 and pT2 stage) and all the patients had wide local excisions peformed. Follow up information was obtained from patient folders in the Department of Radiation Oncology. DA - 2006 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2006 T1 - A study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma TI - A study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma UR - http://hdl.handle.net/11427/3085 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/3085
dc.identifier.vancouvercitationPillay K. A study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Division of Anatomical Pathology, 2006 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/3085en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDivision of Anatomical Pathologyen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherAnatomical Pathologyen_ZA
dc.titleA study to investigate the role of P27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinomaen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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