HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes

dc.contributor.advisorBoulle, Andrewen_ZA
dc.contributor.advisorPienaar, Daviden_ZA
dc.contributor.authorEssel, Vivienen_ZA
dc.date.accessioned2015-08-27T12:36:00Z
dc.date.available2015-08-27T12:36:00Z
dc.date.issued2015en_ZA
dc.description.abstractBackground Sentinel antenatal clinic (ANC) surveys remain a key source of data on HIV prevalence trends. Recently though, with an increase in the uptake of prevention of mother-to-child transmission (PMTCT) programmes, there have been debates on the prospects of using PMTCT data for reporting antenatal HIV prevalence and trends. Aim To describe the HIV prevalence trends for the Western Cape Province and to compare prevalence from ANC surveys to PMTCT programmes. Methods HIV prevalence and 95% confidence intervals were estimated from ANC surveys from 2001-2012 for the province as well as the 6 health districts and the 8 City of Cape Town Metropolitan sub-districts in the province. HIV prevalence from expanded provincial ANC survey sampling was compared to the nationally reported provincial and district estimates, before and after re-weighting to account for differences between the realized sample and updated sampling frame. A regression line was fitted with calendar year included as both a linear and quadratic term to create smoothed trend lines of the change in HIV prevalence over time by province, district, sub-district and age group. A multivariable logistic regression model was fitted to the multi-year ANC survey data to explore associations with HIV prevalence. ANC survey HIV prevalence estimates were compared to those from routinely reported HIV testing data from the PMTCT program for 2009-2012.en_ZA
dc.identifier.apacitationEssel, V. (2015). <i>HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes</i>. (Thesis). University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine. Retrieved from http://hdl.handle.net/11427/13804en_ZA
dc.identifier.chicagocitationEssel, Vivien. <i>"HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes."</i> Thesis., University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine, 2015. http://hdl.handle.net/11427/13804en_ZA
dc.identifier.citationEssel, V. 2015. HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes. University of Cape Town.en_ZA
dc.identifier.ris TY - Thesis / Dissertation AU - Essel, Vivien AB - Background Sentinel antenatal clinic (ANC) surveys remain a key source of data on HIV prevalence trends. Recently though, with an increase in the uptake of prevention of mother-to-child transmission (PMTCT) programmes, there have been debates on the prospects of using PMTCT data for reporting antenatal HIV prevalence and trends. Aim To describe the HIV prevalence trends for the Western Cape Province and to compare prevalence from ANC surveys to PMTCT programmes. Methods HIV prevalence and 95% confidence intervals were estimated from ANC surveys from 2001-2012 for the province as well as the 6 health districts and the 8 City of Cape Town Metropolitan sub-districts in the province. HIV prevalence from expanded provincial ANC survey sampling was compared to the nationally reported provincial and district estimates, before and after re-weighting to account for differences between the realized sample and updated sampling frame. A regression line was fitted with calendar year included as both a linear and quadratic term to create smoothed trend lines of the change in HIV prevalence over time by province, district, sub-district and age group. A multivariable logistic regression model was fitted to the multi-year ANC survey data to explore associations with HIV prevalence. ANC survey HIV prevalence estimates were compared to those from routinely reported HIV testing data from the PMTCT program for 2009-2012. DA - 2015 DB - OpenUCT DP - University of Cape Town LK - https://open.uct.ac.za PB - University of Cape Town PY - 2015 T1 - HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes TI - HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes UR - http://hdl.handle.net/11427/13804 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/13804
dc.identifier.vancouvercitationEssel V. HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes. [Thesis]. University of Cape Town ,Faculty of Health Sciences ,Department of Public Health and Family Medicine, 2015 [cited yyyy month dd]. Available from: http://hdl.handle.net/11427/13804en_ZA
dc.language.isoengen_ZA
dc.publisher.departmentDepartment of Public Health and Family Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.subject.otherPublic Healthen_ZA
dc.titleHIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmesen_ZA
dc.typeMaster Thesis
dc.type.qualificationlevelMasters
dc.type.qualificationnameMMeden_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceThesisen_ZA
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