Genomic medicine in Africa: promise, problems and prospects

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dc.contributor.authorWonkam, Ambroiseen_ZA
dc.contributor.authorMayosi, Bonganien_ZA
dc.date.accessioned2015-11-27T09:33:41Z
dc.date.available2015-11-27T09:33:41Z
dc.date.issued2014en_ZA
dc.description.abstractRemarkable progress has been made in using genomic information to determine how genes are regulated, and how they interact with each other and with the environment to control complex biochemical functions of living organisms in health and disease [1]. This information will have major benefits for the prevention, diagnosis and management of many diseases, including communicable and genetic diseases. In Africa, where infectious diseases are highly prevalent, research on pathogen genomes has enhanced our understanding of disease transmission, virulence mechanisms and avoidance of host defenses [2]. It is anticipated that this information will enable the development of new diagnostic tests, vaccines and therapeutic agents; it is also likely to lead to new approaches for vector control, and reveal why individuals and populations vary in their susceptibility to infectious diseases [1].en_ZA
dc.identifier.apacitationWonkam, A., & Mayosi, B. (2014). Genomic medicine in Africa: promise, problems and prospects. <i>Genome Medicine</i>, http://hdl.handle.net/11427/15401en_ZA
dc.identifier.chicagocitationWonkam, Ambroise, and Bongani Mayosi "Genomic medicine in Africa: promise, problems and prospects." <i>Genome Medicine</i> (2014) http://hdl.handle.net/11427/15401en_ZA
dc.identifier.citationWonkam, A., & Mayosi, B. M. (2014). Genomic medicine in Africa: promise, problems and prospects. Genome medicine, 6(2), 11.en_ZA
dc.identifier.ris TY - Journal Article AU - Wonkam, Ambroise AU - Mayosi, Bongani AB - Remarkable progress has been made in using genomic information to determine how genes are regulated, and how they interact with each other and with the environment to control complex biochemical functions of living organisms in health and disease [1]. This information will have major benefits for the prevention, diagnosis and management of many diseases, including communicable and genetic diseases. In Africa, where infectious diseases are highly prevalent, research on pathogen genomes has enhanced our understanding of disease transmission, virulence mechanisms and avoidance of host defenses [2]. It is anticipated that this information will enable the development of new diagnostic tests, vaccines and therapeutic agents; it is also likely to lead to new approaches for vector control, and reveal why individuals and populations vary in their susceptibility to infectious diseases [1]. DA - 2014 DB - OpenUCT DO - 10.1186/gm528 DP - University of Cape Town J1 - Genome Medicine LK - https://open.uct.ac.za PB - University of Cape Town PY - 2014 T1 - Genomic medicine in Africa: promise, problems and prospects TI - Genomic medicine in Africa: promise, problems and prospects UR - http://hdl.handle.net/11427/15401 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/15401
dc.identifier.urihttp://dx.doi.org/10.1186/gm528
dc.identifier.vancouvercitationWonkam A, Mayosi B. Genomic medicine in Africa: promise, problems and prospects. Genome Medicine. 2014; http://hdl.handle.net/11427/15401.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentDepartment of Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis article is available under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2014 Wonkam and Mayosi; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceGenome Medicineen_ZA
dc.source.urihttp://www.genomemedicine.com/en_ZA
dc.subject.othergenomic informationen_ZA
dc.subject.othergenes regulationen_ZA
dc.subject.othergenes interactionen_ZA
dc.subject.otherbiochemical functionsen_ZA
dc.subject.otherliving organismsen_ZA
dc.subject.otherhealthen_ZA
dc.subject.otherdiseaseen_ZA
dc.titleGenomic medicine in Africa: promise, problems and prospectsen_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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