Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk

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dc.contributor.authorLuke, Amyen_ZA
dc.contributor.authorBovet, Pascalen_ZA
dc.contributor.authorForrester , Terrenceen_ZA
dc.contributor.authorLambert, Estelleen_ZA
dc.contributor.authorPlange-Rhule, Jacoben_ZA
dc.contributor.authorSchoeller, Daleen_ZA
dc.contributor.authorDugas, Laraen_ZA
dc.contributor.authorDurazo-Arvizu, Ramonen_ZA
dc.contributor.authorShoham, Daviden_ZA
dc.contributor.authorCooper, Richarden_ZA
dc.contributor.authorBrage, Sorenen_ZA
dc.contributor.authorEkelund, Ulfen_ZA
dc.contributor.authorSteyn, Neliaen_ZA
dc.date.accessioned2015-11-11T11:52:38Z
dc.date.available2015-11-11T11:52:38Z
dc.date.issued2011en_ZA
dc.description.abstractBACKGROUND: The prevalence of obesity has increased in societies of all socio-cultural backgrounds. To date, guidelines set forward to prevent obesity have universally emphasized optimal levels of physical activity. However there are few empirical data to support the assertion that low levels of energy expenditure in activity is a causal factor in the current obesity epidemic are very limited. METHODS/DESIGN: The Modeling the Epidemiologic Transition Study (METS) is a cohort study designed to assess the association between physical activity levels and relative weight, weight gain and diabetes and cardiovascular disease risk in five population-based samples at different stages of economic development. Twenty-five hundred young adults, ages 25-45, were enrolled in the study; 500 from sites in Ghana, South Africa, Seychelles, Jamaica and the United States. At baseline, physical activity levels were assessed using accelerometry and a questionnaire in all participants and by doubly labeled water in a subsample of 75 per site. We assessed dietary intake using two separate 24-hour recalls, body composition using bioelectrical impedance analysis, and health history, social and economic indicators by questionnaire. Blood pressure was measured and blood samples collected for measurement of lipids, glucose, insulin and adipokines. Full examination including physical activity using accelerometry, anthropometric data and fasting glucose will take place at 12 and 24 months. The distribution of the main variables and the associations between physical activity, independent of energy intake, glucose metabolism and anthropometric measures will be assessed using cross-section and longitudinal analysis within and between sites. DISCUSSION: METS will provide insight on the relative contribution of physical activity and diet to excess weight, age-related weight gain and incident glucose impairment in five populations' samples of young adults at different stages of economic development. These data should be useful for the development of empirically-based public health policy aimed at the prevention of obesity and associated chronic diseases.en_ZA
dc.identifier.apacitationLuke, A., Bovet, P., Forrester , T., Lambert, E., Plange-Rhule, J., Schoeller, D., ... Steyn, N. (2011). Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk. <i>BMC Public Health</i>, http://hdl.handle.net/11427/14852en_ZA
dc.identifier.chicagocitationLuke, Amy, Pascal Bovet, Terrence Forrester , Estelle Lambert, Jacob Plange-Rhule, Dale Schoeller, Lara Dugas, et al "Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk." <i>BMC Public Health</i> (2011) http://hdl.handle.net/11427/14852en_ZA
dc.identifier.citationLuke, A., Bovet, P., Forrester, T. E., Lambert, E. V., Plange-Rhule, J., Schoeller, D. A., ... & Steyn, N. P. (2011). Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk. BMC Public Health, 11(1), 927.en_ZA
dc.identifier.ris TY - Journal Article AU - Luke, Amy AU - Bovet, Pascal AU - Forrester , Terrence AU - Lambert, Estelle AU - Plange-Rhule, Jacob AU - Schoeller, Dale AU - Dugas, Lara AU - Durazo-Arvizu, Ramon AU - Shoham, David AU - Cooper, Richard AU - Brage, Soren AU - Ekelund, Ulf AU - Steyn, Nelia AB - BACKGROUND: The prevalence of obesity has increased in societies of all socio-cultural backgrounds. To date, guidelines set forward to prevent obesity have universally emphasized optimal levels of physical activity. However there are few empirical data to support the assertion that low levels of energy expenditure in activity is a causal factor in the current obesity epidemic are very limited. METHODS/DESIGN: The Modeling the Epidemiologic Transition Study (METS) is a cohort study designed to assess the association between physical activity levels and relative weight, weight gain and diabetes and cardiovascular disease risk in five population-based samples at different stages of economic development. Twenty-five hundred young adults, ages 25-45, were enrolled in the study; 500 from sites in Ghana, South Africa, Seychelles, Jamaica and the United States. At baseline, physical activity levels were assessed using accelerometry and a questionnaire in all participants and by doubly labeled water in a subsample of 75 per site. We assessed dietary intake using two separate 24-hour recalls, body composition using bioelectrical impedance analysis, and health history, social and economic indicators by questionnaire. Blood pressure was measured and blood samples collected for measurement of lipids, glucose, insulin and adipokines. Full examination including physical activity using accelerometry, anthropometric data and fasting glucose will take place at 12 and 24 months. The distribution of the main variables and the associations between physical activity, independent of energy intake, glucose metabolism and anthropometric measures will be assessed using cross-section and longitudinal analysis within and between sites. DISCUSSION: METS will provide insight on the relative contribution of physical activity and diet to excess weight, age-related weight gain and incident glucose impairment in five populations' samples of young adults at different stages of economic development. These data should be useful for the development of empirically-based public health policy aimed at the prevention of obesity and associated chronic diseases. DA - 2011 DB - OpenUCT DO - 10.1186/1471-2458-11-927 DP - University of Cape Town J1 - BMC Public Health LK - https://open.uct.ac.za PB - University of Cape Town PY - 2011 T1 - Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk TI - Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk UR - http://hdl.handle.net/11427/14852 ER - en_ZA
dc.identifier.urihttp://hdl.handle.net/11427/14852
dc.identifier.urihttp://dx.doi.org/10.1186/1471-2458-11-927
dc.identifier.vancouvercitationLuke A, Bovet P, Forrester T, Lambert E, Plange-Rhule J, Schoeller D, et al. Protocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk. BMC Public Health. 2011; http://hdl.handle.net/11427/14852.en_ZA
dc.language.isoengen_ZA
dc.publisherBioMed Central Ltden_ZA
dc.publisher.departmentMRC/UCT RU for Exercise and Sport Medicineen_ZA
dc.publisher.facultyFaculty of Health Sciencesen_ZA
dc.publisher.institutionUniversity of Cape Town
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution Licenseen_ZA
dc.rights.holder2011 Luke et al; licensee BioMed Central Ltd.en_ZA
dc.rights.urihttp://creativecommons.org/licenses/by/2.0en_ZA
dc.sourceBMC Public Healthen_ZA
dc.source.urihttp://www.biomedcentral.com/bmcpublichealth/en_ZA
dc.subject.otherObesityen_ZA
dc.subject.otherSocio-cultural backgroundsen_ZA
dc.subject.otherPhysical activityen_ZA
dc.subject.otherModeling the Epidemiologic Transition Study (METS)en_ZA
dc.subject.otherweight gainen_ZA
dc.subject.otherdiabetesen_ZA
dc.subject.othercardiovascular disease risken_ZA
dc.titleProtocol for the modeling the epidemiologic transition study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risken_ZA
dc.typeJournal Articleen_ZA
uct.type.filetypeText
uct.type.filetypeImage
uct.type.publicationResearchen_ZA
uct.type.resourceArticleen_ZA
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